Results 71 to 80 of about 8,227 (161)

Integrative Identification of Anti‐Photoaging Peptides From Stress‐Tolerant Microorganisms via Machine Learning and KEAP1–NRF2 Docking

Journal of Peptide Science, Volume 32, Issue 8, August 2026.
Novel short‐chain peptides targeting the KEAP1‐NRF2 axis were identified through a multimodal discovery platform combining a stress‐tolerant microbial library with machine learning and molecular docking. These peptides regulate collagen synthesis and reduce MMP1/9 levels in human fibroblasts, providing significant protection against photoaging ...
Hanui Lee, Gyeong Han Jeong, Ji Wan Choi, Taehwan Kim, Younhee Shin, Jaewon Lim, Kwang‐Woo Jung, Byung Yeoup Chung, Seung Sik Lee   +8 more
wiley   +1 more source

Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

Frontiers in Pharmacology
Background:Sophora flavescens, a traditional Chinese medicine for treating conditions associated with abnormal skin pigmentation, contains flavonoids with inhibitory effects on tyrosinase.
Fenling Fan, Lanqing Chen, Caihong Chen, Song Ang, Justin Gutkowski, Navindra P. Seeram, Hang Ma, Dongli Li, Dongli Li   +8 more
doaj   +1 more source

Neobavaisoflavone Inhibits Melanogenesis through the Regulation of Akt/GSK-3β and MEK/ERK Pathways in B16F10 Cells and a Reconstructed Human 3D Skin Model

Molecules, 2020
Previous studies have confirmed the anti-melanogenic effect of the aerial part of Pueraria lobata, however, due to its inherent color, P. lobata has limited commercial use. In this study, an extract (GALM-DC) of the aerial part of P.
Da Eun Kim, Bo Yoon Chang, Sang Ok Ham, Youn Chul Kim, Sung Yeon Kim   +4 more
doaj   +1 more source

Low Sunscreen Awareness and Misconceptions in Skin of Colour With Acne‐Related Post‐Inflammatory Hyperpigmentation: A Cross‐Sectional Study Highlighting the Need for Targeted Education

Australasian Journal of Dermatology, Volume 67, Issue 5, Page e299-e306, August 2026.
ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) is a frequent sequela of acne in patients with skin of colour (SOC). While sunscreen is widely recommended for PIH prevention, little is known about real‐world sunscreen practices in this group. This study aimed to evaluate sunscreen use, barriers and factors influencing adherence
Xiaozhun Hang, Davin Sui Lim, Lisa Byrom
wiley   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, Volume 48, Issue 4, Page 780-797, August 2026.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Glutathione Trisulphide Improves Skin Brightness with Anti-Melanogenesis Effects and Maintains Intracellular Persulphide Levels

Cosmetics
Melanin, the principal component of skin pigmentation, is produced through tyrosinase activity. Recently, supersulphides have been identified in human cells and found to play a role in maintaining cellular activities.
Yoshiaki Uchida, Toshiya Sato
doaj   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, Volume 48, Issue 4, Page 884-910, August 2026.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

Preparation, identification, and anti-melanogenesis activity of royal jelly protein peptides

Journal of Functional Foods
Excessive melanogenesis leads to hyperpigmentation-related skin disorders. To develop safe and effective anti-melanogenic agents, an ultrafiltered fraction RJPH-1 (MW 
Jiayi Liang, Chengliang Guo, Zhiwen Li, Jing Bi, Ruiming Wang, Piwu Li, Xiaohui Yang   +6 more
openaire   +2 more sources

Deciphering the molecular pathway of an asiaticosiderich fraction of Centella asiatica as an anti-melanogenesis agent

Journal of Herbmed Pharmacology
Introduction: Melanin is a defense against UV radiation; however, it leads to significant cosmetic issues mainly melasma and hyperpigmentation. This study evaluated the potential effect of ethyl acetate (EtOAc) fraction of Centella asiatica extract in vitro inhibition activity against tyrosinase (TYR). Bioinformatics and in silico experiments were also
Agustina Setiawati, Brigitta Amanda Maharani, Putu Addelia Puspa Sari, K. Ariex Widyantara, Bakti Wahyu Saputra, Rifki Febriansah, Rini Dwiastuti   +6 more
openaire   +2 more sources

The Effects of on Anti-Cellular Oxidants and Melanogenesis Inhibition in α-MSH-stimulated and UV Irradiated B16 Melanoma Cells

Natural Product Communications, 2014
The purposes of this study were to investigate the inhibitory effects of Salacia reticulata Tul. root extract on cellular oxidants and melanogenesis in B16 melanoma cells. Cells treated with non-toxic doses of S. reticulata root extract were investigated
Prasit Sirwannalert, Ryusho Kariya, Ikuko Suzu, Seiji Okada   +3 more
doaj   +1 more source