Results 51 to 60 of about 1,448,593 (185)

Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos

Research in Pharmaceutical Sciences, 2020
Background and purpose: Excessive melanin production caused by overactive tyrosinase (TYR) enzyme results in several dermatological problems. The TYR inhibitor, derived from metabolite changes during fermentation, has been well recognized for ...
Teerapat Rodboon, Sasithorn Sirilun, Seiji Okada, Ryusho Kariya, Thapana Chontananarth, Prasit Suwannalert   +5 more
doaj   +1 more source

Modulating skin colour: role of the thioredoxin and glutathione systems in regulating melanogenesis

, 2021
Different skin colour among individuals is determined by the varying amount and types of melanin pigment. Melanin is produced in melanocytes, a type of dendritic cell located in the basal layer of the epidermis, through the process of melanogenesis ...
Lu, Yaoying, Di Trapani, Giovanna, Tonissen, Kathryn F   +2 more
core   +1 more source

Investigation of phenyllactic acid as a potent tyrosinase inhibitor produced by probiotics

Current Research in Food Science, 2023
Melanogenesis is responsible for skin pigmentation and the enzymatic browning of foods. Tyrosinases play a major role in melanin synthesis, and many attempts have been made to identify new natural tyrosinase inhibitors, but few have sought to do in ...
Minhye Shin, Van-Long Truong, Minjee Lee, Donggyu Kim, Myun Soo Kim, Hana Cho, Young Hoon Jung, Jungwoo Yang, Woo Sik Jeong, Younghoon Kim   +9 more
doaj   +1 more source

Effect of Chicken Egg White-Derived Peptide and Hydrolysates on Abnormal Skin Pigmentation during Wound Recovery

Molecules, 2022
Abnormal skin pigmentation commonly occurs during the wound healing process due to the overproduction of melanin. Chicken egg white (CEW) has long been used to improve skin health.
Pei-Gee Yap, Chee-Yuen Gan, Idanawati Naharudin, Tin-Wui Wong   +3 more
doaj   +1 more source

The mechanisms of melanogenesis inhibition by glabridin: molecular docking, PKA/MITF and MAPK/MITF pathways

Food Science and Human Wellness, 2023
Glabridin is the main ingredient of hydrophobic fraction in licorice extract and has been shown to have anti-melanogenesis activity in skins. However, the underlying mechanism(s) remain not completely understood.
Chunxing Pan, Xiaoying Liu, Yating Zheng, Zejun Zhang, Yongliang Li, Biao Che, Guangrong Liu, Lanyue Zhang, Changzhi Dong, Haji Akber Aisa, Zhiyun Du, Zhengqiang Yuan   +11 more
doaj   +1 more source

The leaf extract of Mallotus japonicus and its major active constituent, rutin, suppressed on melanin production in murine B16F1 melanoma

Asian Pacific Journal of Tropical Biomedicine, 2015
Objective: To find anti-melanogenesis materials used in whitening cosmetics. Methods: The ethanolic leaf extract of Mallotus japonicus (M. japonicus) having an anti-melanogenesis activity was separated by a sephadex LH-20 chromatography.
Junsei Taira, Eito Tsuchida, Masatsugu Uehara, Natsuko Ohhama, Wakana Ohmine, Takayuki Ogi   +5 more
doaj   +1 more source

Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation. [PDF]

Exp Dermatol
ABSTRACT The circadian clock regulates multiple physiological processes in the skin, including local hormone synthesis and pigmentation. However, how circadian regulation interacts with epidermal endocrine signalling in melanocytes remains unclear.
Zhu A, Yang L, Lai S, Yang F, Tsuruta D, Katayama I.   +5 more
europepmc   +2 more sources

CHARACTERIZATION OF THE ROLE OF STIM1 IN MELANOGENESIS

, 2023
reservedIntracellular Ca2+ homeostasis plays a key role in the control of melanogenesis, the process responsible for the biogenesis of melanosomes, and for melanin accumulation.
DE CIA, ISABELLA
core  

Aspacochioside C from Asparagus cochinchinensis attenuates eumelanin synthesis via inhibition of TRP2 expression

Scientific Reports, 2023
Aspacochioside C (ACC) is a steroidal saponin isolated from Asparagus cochinchinensis. Steroidal saponins, such as pseudoprotodioscin and dioscin, are known to inhibit melanogenesis, but the role of ACC in melanogenesis remains unknown.
Silvia Yunmam, Hae Ran Lee, Seong Min Hong, Ji-Young Kim, Tong Ho Kang, Ai Young Lee, Dae Sik Jang, Sun Yeou Kim   +7 more
doaj   +1 more source

Inonotus obliquus Extract as An Inhibitor of α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells

Cosmetics, 2019
Melanogenesis is a biosynthetic pathway that produces the pigment melanin in human skin. The catalyzation of the key enzyme tyrosinase is the first step in melanogenesis, and the downregulation of tyrosinase enzyme activity is the most reported method ...
Eun Ji Lee, Hwa Jun Cha
doaj   +1 more source