Results 41 to 50 of about 8,700 (155)

Inonotus obliquus Extract as An Inhibitor of α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells

Cosmetics, 2019
Melanogenesis is a biosynthetic pathway that produces the pigment melanin in human skin. The catalyzation of the key enzyme tyrosinase is the first step in melanogenesis, and the downregulation of tyrosinase enzyme activity is the most reported method ...
Eun Ji Lee, Hwa Jun Cha
doaj   +1 more source

Exploring the Biological Functions and Anti-Melanogenesis of Phallus indusiatus for Mushroom-Based Cosmetic Applications

Cosmetics, 2023
Phallus indusiatus, or bamboo mushroom, has been reported for its nutraceutical properties, while its cosmeceutical properties remain unclear. In this study, we conducted extractions of whole, fresh P. indusiatus using both aqueous and ethanolic methods.
Theeraraksakul, Kanyanat, Jaengwang, Kittitat, Choowongkomon, Kiattawee, Tabtimmai, Lueacha   +3 more
openaire   +2 more sources

Aspacochioside C from Asparagus cochinchinensis attenuates eumelanin synthesis via inhibition of TRP2 expression

Scientific Reports, 2023
Aspacochioside C (ACC) is a steroidal saponin isolated from Asparagus cochinchinensis. Steroidal saponins, such as pseudoprotodioscin and dioscin, are known to inhibit melanogenesis, but the role of ACC in melanogenesis remains unknown.
Silvia Yunmam, Hae Ran Lee, Seong Min Hong, Ji-Young Kim, Tong Ho Kang, Ai Young Lee, Dae Sik Jang, Sun Yeou Kim   +7 more
doaj   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica

Natural Product Research, 2021
Three glycosylated stilbenes (1–3), two anthraquinones (4, 5), one lignan (6), five tannins (7–11), two amino acids (12, 13), and one auronol (14) were isolated from the root of Ampelopsis japonica. All compounds, except for 4, 6, and 11 were obtained from this species for the first time.
Chia-Lin Lee, Yun-Lian Jhan, Hsiu-Mei Chiang, Yi-Hung Chen, Chao-Jung Chen, Yuan-Shiun Chang   +5 more
openaire   +2 more sources

Calebin-A, a Curcuminoid Analog Inhibits α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells

Cosmetics, 2019
Hyperpigmentation skin disorders comprise melasma, age spots, and post-inflammatory hyperpigmentation. They are characterized by an aberrant upregulation of melanin pigment and pose a significant burden aesthetically.
Shilpi Goenka, Kalyanam Nagabhushanam, Muhammed Majeed, Sanford R. Simon   +3 more
doaj   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Glutathione Trisulphide Suppresses UVB-Induced Melanogenesis and Improves Skin Brightness in a Three-Dimensional Skin Model

Cosmetics
Ultraviolet B (UVB) irradiation induces hyperpigmentation and contributes to skin photoaging. Glutathione trisulphide (GSSSG), a naturally occurring supersulphide with anti-inflammatory and antioxidant properties, has been shown to suppress α-melanocyte ...
Yoshiaki Uchida, Katsuya Sato, Masayuki Ito, Toshiya Sato   +3 more
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Search for Skin-whitening Agent from Plants and the Molecular Targets in Melanogenesis Pathway of Active Compounds

Natural Product Communications, 2014
In our research program for discovering novel skin-whitening materials, screening of extracts from flowers of some Prunus species was performed using an anti-tyrosinase assay. Among the tested plants, the flowers of P.
Kazuya Murata, Keisuke Takahashi, Haruka Nakamura, Kimihisa Itoh, Hideaki Matsuda   +4 more
doaj   +1 more source