Results 111 to 120 of about 145,320 (184)

Anti-drug antibody responses.

, 2019
Specific anti-3BNC117 antibody titers (top panel) and anti-10-1074 antibody titers (bottom panel) at selected time points following the administration of 3BNC117 plus 10–1074 are displayed for individuals participants.
Margaret E. Ackerman (7163789), Julio C. C. Lorenzi (7163768), Shu Lin (78544), Cecilia Unson-O’Brien (7163759), Katrina Millard (7163750), Marina Caskey (221449), Nicole L. Yates (7163783), Michel C. Nussenzweig (7163795), Bryan Mayer (5506541), Kelly E. Seaton (7163780), Rebeka Levin (7163756), Irina Shimeliovich (7163765), Allan C. deCamp (3687397), Anna Tse (650526), Alicia Sato (235292), Allison L. Butler (7163747), Joshua A. Weiner (155918), Yehuda Z. Cohen (7163744), Jill Horowitz (7163771), Michael S. Seaman (155998), Georgia D. Tomaras (7163792), Maggi Witmer-Pack (7163753), Roshni Patel (7163762), Lindsey R. Baden (7163786), Stephen R. Walsh (7163774), Chelsey Bennett (7163777)   +25 more
core   +1 more source

Schematic of epitope spreading of PLA2R.

BackgroundM-type phospholipase A2 receptor (PLA2R) is the major autoantigen in adult idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R domains have been identified, the clinical value of these domains recognized by anti ...
Yuan Qin (260617), Zhigang Hu (477325), Xiumei Zhou (126818), Qingqing Wu (1969732), Xue Yang (144876), Bo Lin (116835), Zijian Huang (10776416), Xiaobin Liu (344083), Liang Wang (23021), Ting Li (117885), Jing Xue (170229), Leting Zhou (12062753), Biao Huang (215504), Huiming Sheng (485213)   +13 more
core   +1 more source

Double Trouble in the Basement! A Case of PLA2R-Associated Membranous Nephropathy with Atypical Anti-Glomerular Basement Membrane Disease

Introduction: Concurrent atypical anti-glomerular basement membrane (anti-GBM) disease with membranous nephropathy is a rare occurrence. Compared to typical anti-GBM disease, atypical anti-GBM disease is often seronegative, with a mild disease ...
David Lyu, Steffi Sathiyaraj, Theresa Thurston, Ali R. Khan, Renuka Tolani, Luan Truong, Shane A. Bobart, Ziad M. El-Zaatari, Angelina Edwards   +8 more
core   +1 more source

Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody

Scientific Reports
Patients with nephrotic syndrome, particularly those with primary membranous nephropathy (pMN), are at a heightened risk of thromboembolic events.
Zihan Zhai, Yanhong Guo, Lu Yu, Yulin Wang, Liuwei Wang, Qiuhong Li, Yapei Yuan, Lin Tang   +7 more
doaj   +1 more source

Ofatumumab: a novel monoclonal anti-CD20 antibody

, 2010
Thomas S LinGlaxoSmithKline Oncology R&D, Collegeville, PA, USAAbstract: Ofatumumab, a novel humanized monoclonal anti-CD20 antibody, was recently approved by the FDA for the treatment of fludarabine and alemtuzumab refractory chronic lymphocytic
Thomas S Lin
core  

SP194SERUM ANTI-PLA2R ANTIBODIES IN GLOMERULONEPHRITIS- ONE CENTRE EXPERIENCE

Nephrology Dialysis Transplantation, 2019
Dagna Rukasz, Katarzyna Koscielska-Kasprzak, Marta Myszka-Kozlowska, Magdalena Krajewska   +3 more
openaire   +1 more source

Advances in the pathogenesis and clinical applications of PLA2R-associated membranous nephropathy

Membranous nephropathy is one of the main pathological types of nephrotic syndrome. PLA2R（phospholipase A2 receptor）associated membranous nephropathy is the predominant type of primary membranous nephropathy， also known as idiopathic membranous ...
Sun Miao-xin, Zhao Xin-cheng, Li Zi-wei, Li Yun-xia, Chai Wen-xiu, Cai Pan-pan, Xin Ye, Duan Li-ping, Wu Hao-wen, Wang Ding-ding   +9 more
core   +1 more source

Clinicopathological characteristics and outcomes of PLA2R related idiopathic membranous nephropathy in patients with seronegative PLA2R antibodies

Idiopathic membranous nephropathy (IMN) with deposits of phospholipase A2 receptor (PLA2R) antigen in glomerular tissue (GAg+) but no circulating serum PLA2R antibody (SAb−) has been reported.
Yang Shen (66591), Yanchun Li (248761), Lijie Ma (755998), Qianmei Sun (17850550), Xue Li (285380)   +4 more
core   +1 more source

Is Rituximab Suitable for Patients with Idiopathic Membranous Nephropathy Who are Seronegative for Anti-PLA2R Antibody? [PDF]

Drug Des Devel Ther
Yang Y, Xie X, Yuan F, Zeng F, Wang Y, Zhang R, Yan W, Luo K, Ren D, Xu G.   +9 more
europepmc   +1 more source

Differences in serum anti-PLA2R antibody determination in Uygur patients with idiopathic membranous nephropathy in Xinjiang

, 2018
Objective To detect the sensitivity and specificity of anti-PLA2 R antibodies in Uygur patient with idiopathic membranous nephropathy（IMN）,understand whether the serum anti-PLA2 R antibody can be regarded as the biomarker in Uygur patients with IMN,then study whether there are differences in the expression of anti-PLA2 R antibody between Uygurs and ...
ZHANG Jin, LU Chen, ZHANG Jing-jing
openaire   +1 more source