Results 101 to 110 of about 145,320 (184)

Supplementary Material for: Optimal Value for Serum Anti-PLA2R Antibody in Primary Membranous Nephropathy: A Multicenter Observational Study

, 2022
Introduction: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is highly specific for primary membranous nephropathy (PMN). Here, we compare the diagnostic value of different circulating PLA2R-Ab cutoff titers in multicenter cohorts, with particular ...
Luan S. (12223319), Cui Z. (2945943), Chen J. (2954172), Wang D. (3939827), Zhang M. (3218208), Liu Y. (597977), Lian Y. (11568802), Zhao M. (2945937), Mi J. (12223322), Li J. (2831522), Wei X. (4133860), Jia X. (5619461), Xu D. (7571108)   +12 more
core   +1 more source

Serum anti-PLA2R negativity does not exclude glomerular PLA2R expression in primary membranous nephropathy

Biomolecules & Biomedicine
Primary membranous nephropathy (pMN) is a principal cause of nephrotic syndrome in adults. The identification of the M-type phospholipase A2 receptor (PLA2R) antigen has significantly advanced non-invasive management; however, the precise clinical ...
Şenay Yıldırım, Ayça İnci, Ayşe Karaduru Avcı, Lütfullah Zahit Koç, Döndü Nergiz, Üstün Yılmaz   +5 more
doaj   +1 more source

Exploring glomeruli and renal tubules transcriptomic data: Crucial role of the AASS gene in membranous nephropathy

Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.
Congcong Jiao, Yuxin Zhao, Yang Shao, Haoshen Feng, Cong Ma, Xiangnan Hao, Xiaomei Liu, Junjun Luan, Xu Yang, Hua Zhou   +9 more
wiley   +1 more source

Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cases

Renal Failure
Background This retrospective study aims to investigate the prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy (HBV-MN).Methods Clinicopathologic and serologic records of ...
Haitao Lu, Qianqian Xu, Guming Zou, Hongmei Gao, Yue Yang, Wenge Li, Li Zhuo   +6 more
doaj   +1 more source

Anti-Phospholipase A2 receptor antibody titer predicts post-rituximab outcome of membranous nephropathy

, 2015
Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary membranous nephropathy (MN), even after other treatments have failed.
T. Pellé, Ruggenenti, Piero, Remuzzi, Giuseppe, H. Debiec, F. Suardi, Gaspari, Flavio, F. Gaspari, Ronco, Pierre, Benigni, Ariela, Ruggiero, Barbara, G. Remuzzi, S. Orisio, Suardi, Flavio, Chianca, Antonietta, Gagliardini, Elena, P. Ronco, Pellé, Timotheé, Orisio, Silvia, A. Chianca, A. Benigni, Debiec, Hanna, E. Gagliardini, P. Ruggenenti, B. Ruggiero   +23 more
core   +1 more source

Cyclophosphamide induced early remission and was superior to rituximab in idiopathic membranous nephropathy patients with high anti-PLA2R antibody levels. [PDF]

BMC Nephrol, 2023
Xue C, Wang J, Pan J, Liang C, Zhou C, Wu J, Song S, Cui L, Zhang L, Liu Y, Dai B.   +10 more
europepmc   +1 more source

Anticorps anti-EPN et anti-PLA2R dans les glomérulopathies extramembraneuses: Le point en 2014

, 2015
Membranous nephropathy (MN) is the most common cause for nephrotic syndrome in adults and occurs as an idiopathic (primary) or secondary disease. Since the early 2000's, substantial advances have been made in the understanding of the molecular bases of ...
Broeders, Emine Nilufer, Nortier, Joëlle, Pozdzik, Agnieszka, Ronco, Pierre, Husson, Cécile, Rorive, Sandrine, Brochériou, Isabelle, Debiec, Hanna, Le Moine, Alain   +8 more
core  

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L, Bulmer-Thomas, B., Banyard, AC, Selden, D., Altmann, F, Craig van Dolleweerd (406086), David Selden (4911475), Selden, D, Ashley C Banyard (16267520), Both, L., Banyard, A.C., Edward Wright (4468198), Bulmer-Thomas, B, Fooks, AR, Friedrich Altmann (33138), Wright, E, van Dolleweerd, C., Fooks, A.R., Ma, J.K.C., Julian K C Ma (16267529), Leonard Both (16267517), van Dolleweerd, C, Ma, JK, Wright, E., Altmann, F., Anthony R Fooks (16267526), Bianca Bulmer-Thomas (16267523)   +26 more
core   +1 more source

Anti-PLA₂R Antibody Development During NELL1-Associated Membranous Glomerulonephritis Treatment: A Case Report. [PDF]

Kidney Med, 2023
Inoue D, Uchida T, Komatsu S, Sugisaki K, Yamada M, Ogawa H, Ishizu A, Oda T.   +7 more
europepmc   +1 more source

Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin domains 1 and 6-7-8 in patients with idiopathic membranous nephropathy.

PLoS ONE
BackgroundM-type phospholipase A2 receptor (PLA2R) is the major autoantigen in adult idiopathic membranous nephropathy (IMN). Although reactive epitopes in the PLA2R domains have been identified, the clinical value of these domains recognized by anti ...
Xiaobin Liu, Jing Xue, Ting Li, Qingqing Wu, Huiming Sheng, Xue Yang, Bo Lin, Xiumei Zhou, Yuan Qin, Zijian Huang, Leting Zhou, Liang Wang, Zhigang Hu, Biao Huang   +13 more
doaj   +1 more source