Results 81 to 90 of about 2,423,946 (178)

Comparison of the prevalence of serum anti-PLA2R Abs with glomerular PLA2R Ag expression in IMN patients.

, 2016
Comparison of the prevalence of serum anti-PLA2R Abs with glomerular PLA2R Ag expression in IMN patients.
Tomohiro Saito (659385), Masayuki Iyoda (425962), Kei Hihara (3161526), Yasutaka Yamamoto (425969), Shohei Tachibana (3161523), Kei Matsumoto (425965), Ken Iseri (659386), Yukihiro Wada (425968), Takanori Shibata (425963), Taihei Suzuki (425961)   +9 more
core   +1 more source

Bilateral drusenoid deposits with subretinal fluid and cystoid macular edema in a serum anti-phospholipase A2 receptor antibody positive patient: A case report

Heliyon
Introduction: Phospholipase A2 receptor (PLA2R) is a major target antigen in idiopathic membranous nephropathy (IMN). IMN was often reported to have retinal vascular abnormalities secondary to hypercoagculability or hypertension.
Hailiang Wu, Lanjing Liu, Li Yan, Na Zhao, Wei Yan   +4 more
doaj   +1 more source

Modified Guizhi Plus Huangqi Decoction Improves Antiphospholipase A2 Receptor Antibody–Induced Podocyte Injury Through Modulating Autophagy‐Related Markers via AMPK/mTOR Pathway

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Phospholipase A2 receptor (PLA2R)–associated membranous nephropathy (MN) is a primary cause of nephrotic syndrome in adults. Modified Guizhi plus Huangqi decoction (MGPHD) has been clinically effective for PLA2R MN. This basic study was designed to investigate the efficacy and mechanisms of MGPHD in treating PLA2R MN.
Manxia Huang, Yangpu Li, Zhishu Yang, Yunxin Lin, Zhuoting Liu, Zilan Jiang, Tingting Tan, Xinhui Liu, Youjia Zeng, Yue Xu   +9 more
wiley   +1 more source

High‐Titer Antinuclear Antibody Defines a Distinct IgG4‐Related Disease Subset With Predilection for Lung and Kidney Involvement

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Objective This study investigated whether antinuclear antibody (ANA) positivity identifies a distinct clinical phenotype in IgG4‐related disease (IgG4‐RD), characterized by specific organ involvement patterns. Methods We conducted a cohort study of patients diagnosed with IgG4‐RD (2016–2024). Based on indirect immunofluorescence (IIF) results, patients
Jie Zhang, Yurong Zhao, Yiwen Wang, Chao Xue, Lidong Hu, Jianglin Zhang, Jian Zhu   +6 more
wiley   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, Volume 9, Issue 9, September 2025.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Interpretation and Clinical Value of Serum Anti-PLA2R-Antibody Testing

The Journal of Applied Laboratory Medicine, 2021
Prapa, Pattrapornpisut, Vathany, Kulasingam, Heather N, Reich   +2 more
openaire   +2 more sources

Complement activation products in the circulation and urine of primary membranous nephropathy

BMC Nephrology, 2019
Background Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation
Mu-fan Zhang, Jing Huang, Yi-miao Zhang, Zhen Qu, Xin Wang, Fang Wang, Li-qiang Meng, Xu-yang Cheng, Zhao Cui, Gang Liu, Ming-hui Zhao   +10 more
doaj   +1 more source

Monthly mini-dose rituximab for primary anti-PLA2R-positive membranous nephropathy: a personalized approach

, 2023
Background The currently recommended dose of rituximab for primary membranous nephropathy is as high as that for lymphoma. However, the clinical manifestations of membranous nephropathy vary widely.
Song Wang, Wenhan Bao, Sijia Zhou, Yue Wang, Zhuan Cui, Danxia Zheng, Zhenling Deng   +6 more
core   +1 more source

Association between triglyceride-glucose index and treatment response in primary membranous nephropathy: a retrospective cohort study

Renal Failure
Background/Objectives The triglyceride-glucose (TyG) index, a marker of insulin resistance, has been linked to chronic kidney disease and proteinuria severity, but its prognostic value for treatment response in primary membranous nephropathy (PMN) is ...
Wei Chen, Tan Hou, Weimin Yu
doaj   +1 more source

Outcomes of primary membranous nephropathy based on serum anti-phospholipase A2 receptor antibodies and glomerular phospholipase A2 receptor antigen status: a retrospective cohort study

Renal Failure, 2020
Introduction Primary membranous nephropathy (PMN) is associated with the anti-phospholipase A2 receptor (anti-PLA2R) antibody in 70% of cases. Some anti-PLA2R-negative patients have the PLA2R antigen in renal tissue.
Peihong Yin, Junxian Wang, Wenyi Liang, Linda Zhan, Yuanhao Liu, Jian Lin, Xiaohong Chen, Yingqin He, Hongyun Jian, Zhibin Xie, Xiaofan Tan, Qing Ye, Fengxian Huang   +12 more
doaj   +1 more source