Results 61 to 70 of about 145,320 (184)

The Spectrum and Temporal Trends of Glomerular Diseases in Saudi Arabia: A Systematic Review of Biopsy‐Based Studies

International Journal of Nephrology, Volume 2026, Issue 1, 2026.
Purpose This systematic review aims to synthesize data from biopsy‐based studies to quantify the epidemiology, regional variations, and temporal trends of glomerular diseases (GDs) in Saudi Arabia. Methods We conducted a systematic search using PubMed, MEDLINE, the Cochrane Library, and Google Scholar to identify relevant studies published up to ...
Manal E. Alotaibi, Laila A. Alharbi, Fahd Almalki, Waleed Alotaibi, Ibrahim Tawhari, Mutlaq Alotaibi, Harleen Khatra   +6 more
wiley   +1 more source

Expression of phospholipase A2 receptor and IgG4 in patients with membranous nephropathy

Vascular Health and Risk Management, 2018
Lei Liu,1 Baochao Chang,1 Xueping Wu,1 Yaling Guo,1 Yan Pan,1 Lijuan Yang2 1Department of Nephrology, The First Affiliated Hospital of Bengbu Medical College, Anhui, People’s Republic of China; 2Department of Physiology, Bengbu Medical College ...
Liu L, Chang B, Wu X, Guo Y, Pan Y, Yang L   +5 more
doaj  

Effect of Glomerular Mannose-Binding Lectin Deposition on the Prognosis of Idiopathic Membranous Nephropathy

Kidney & Blood Pressure Research, 2020
Objective: Co-deposition of mannose-binding lectin (MBL) and IgG4 anti-phospholipase A2 receptor (anti-PLA2R) autoantibodies under subepithelial cells has been observed in patients with idiopathic membranous nephropathy (iMN), but the relationships of ...
Ying Zhang, Yipeng Liu, Liming Liang, Liyan Liu, Xueqing Tang, Lijun Tang, Ping Chen, Juan Chen, Zunsong Wang, Wei Cao, Qinlan Chen, Na Zhao, Dongmei Xu   +12 more
doaj   +1 more source

HLA Profiles of Patients With Chronic Kidney Disease in Central South Africa

International Journal of Nephrology, Volume 2026, Issue 1, 2026.
Background The human leucocyte antigen (HLA) complex has been associated with the susceptibility of several hundred human diseases, increasingly so with kidney disease. HLA data are under‐represented in South Africa, and thus, their contribution to disease characterisation remains poorly understood.
Walter Janse van Rensburg, Kirsten Lange, Feziwe Bisiwe, Jean Kloppers, Srijoni Sengupta   +4 more
wiley   +1 more source

Anti-EJ Antibody-positive Anti-synthetase Syndrome Associated with Retroperitoneal Sarcoma [PDF]

, 2020
A 74-year-old man with interstitial lung disease (ILD) underwent surgical excision of a growing retroperitoneal tumor and was diagnosed with spindle cell sarcoma. Just after the surgery, skin eruption and muscle weakness emerged.
Kobayashi, Kazuma, Adachi, Tomohiko, Hidaka, Masaaki, Takatsuki, Mitsuhisa, Kawakami, Atsushi, Abe, Kuniko, Fujita, Yuya, Kuwana, Masataka, Eguchi, Susumu, Fukui, Saeko, Fukui, Shoichi, Iwamoto, Naoki   +11 more
core   +1 more source

A study on the association between serum antiphospholipase A2 receptor antibodies and the hypercoagulable state in Chinese patients with primary membranous nephropathy

Renal Failure
Primary membranous nephropathy (PMN) increases venous thromboembolism (VTE) risk. This study investigated the relationship between anti-phospholipase A2 receptor (PLA2R) antibody status and coagulation profiles via thromboelastography (TEG) in PMN ...
Baolian Liu, Qiuyue Qin, Shuilin He
doaj   +1 more source

Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in Idiopathic Membranous Nephropathy

Frontiers in Immunology, 2022
BackgroundThe anti-phospholipase A2 receptor (PLA2R) antibody is a non-invasive diagnostic tool and prognosis predictor of idiopathic membranous nephropathy (IMN). Baseline hypercholesterolemia independently predicts proteinuria outcomes in IMN patients.
Lei Dong, Yue-qiang Li, Shui-ming Guo, Gang Xu, Wang Wei, Min Han   +5 more
doaj   +1 more source

Modified Guizhi Plus Huangqi Decoction Improves Antiphospholipase A2 Receptor Antibody–Induced Podocyte Injury Through Modulating Autophagy‐Related Markers via AMPK/mTOR Pathway

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Phospholipase A2 receptor (PLA2R)–associated membranous nephropathy (MN) is a primary cause of nephrotic syndrome in adults. Modified Guizhi plus Huangqi decoction (MGPHD) has been clinically effective for PLA2R MN. This basic study was designed to investigate the efficacy and mechanisms of MGPHD in treating PLA2R MN.
Manxia Huang, Yangpu Li, Zhishu Yang, Yunxin Lin, Zhuoting Liu, Zilan Jiang, Tingting Tan, Xinhui Liu, Youjia Zeng, Yue Xu   +9 more
wiley   +1 more source

Anti-phospholipase A2 receptor in Non-lupus Patients with Membranous Nephropathy and Crescents

Glomerular Diseases, 2021
Introduction: Anti-phospholipase A2 receptor (PLA2R) is detected in approximately 70% of biopsies of “primary” membranous nephropathy (MN). Crescents in MN in non-lupus patients suggest additional injury, such as antineutrophil cytoplasmic antibody ...
Yiqin Zuo, Livia Barreira Cavalcante, James Monroe Smelser, Neil Sanghani, Jamie P. Dwyer, Julia Breyer Lewis, Agnes B. Fogo   +6 more
doaj   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, Volume 9, Issue 9, September 2025.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source