Results 61 to 70 of about 2,423,946 (178)

Anti-PLA2R antibody levels and clinical risk factors for predicting relapse in primary membranous nephropathy [PDF]

Front Immunol
Objectives To explore the predictive value of anti-phospholipase A2 receptor (PLA2R) antibody levels and clinical risk factors for relapse in patients with primary membranous nephropathy (pMN) who achieved remission after immunosuppressive therapy ...
Wang H, Ma H, Wang H.
europepmc   +2 more sources

The Spectrum of Biopsy‐Proven Renal Diseases in Chinese Elderly Patients and Its Temporal Shift Over 20 Years: A Retrospective Cohort Study

AGING MEDICINE, Volume 9, Issue 3, Page 258-264, June 2026.
This 20‐year retrospective study reveals a significant increase in renal biopsy utilization and a pivotal shift in biopsy‐proven renal disease among Chinese elderly patients. Secondary glomerular nephropathy (particularly diabetic nephropathy and hypertensive nephropathy) has surpassed primary glomerular nephropathy as the leading biopsy‐proven ...
Shasha Han, Lengnan Xu, Ying Sun, Fang Fang, Xin Liu   +4 more
wiley   +1 more source

DataSheet_1_Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in Idiopathic Membranous Nephropathy.docx

, 2022
BackgroundThe anti-phospholipase A2 receptor (PLA2R) antibody is a non-invasive diagnostic tool and prognosis predictor of idiopathic membranous nephropathy (IMN). Baseline hypercholesterolemia independently predicts proteinuria outcomes in IMN patients.
Lei Dong (165252), Shui-ming Guo (12889358), Gang Xu (219455), Wang Wei (2074669), Yue-qiang Li (12889355), Min Han (56772)   +5 more
core   +1 more source

Clinical usefulness of autoantibodies to M-type phospholipase A2 receptor (PLA2R) for monitoring disease activity in idiopathic membranous nephropathy (IMN)

, 2016
Autoantibodies to M-type phospholipase A2 receptor (PLA2R) are specific markers of idiopathic membranous nephropathy (IMN). They can differentiate IMN from other glomerular diseases and primary from secondary forms of MN.
Stellato, Tiziana, Napodano, Pietro, Londrino, Francesco, Ortisi, Giuseppe, Radice, Antonella, Sinico, Renato Alberto, Trezzi, Barbara, Maggiore, Umberto, Pesce, Gianpaola, D'Amico, Marco, Ravera, Federica, Santoro, Domenico, Pregnolato, Francesca, Rolla, Davide   +13 more
core   +2 more sources

Diagnostic performance of time-resolved fluoroimmunoassay based anti-phospholipase A2 receptor antibody detection for primary membranous nephropathy

Scientific Reports
Detection of anti-phospholipase A2 receptor (PLA2R) antibody levels is a non-invasive method for the diagnosis of primary membranous nephropathy (PMN).
Zhenling Deng, Yuanlin Qu, Tianyu Zheng, Biao Huang, Yue Wang, Danxia Zheng   +5 more
doaj   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham, Leja Hamza, Azeb Kebede, Daniel Rebuma Bekele, Zekarias Amdemariam   +4 more
wiley   +1 more source

Effect of Glomerular Mannose-Binding Lectin Deposition on the Prognosis of Idiopathic Membranous Nephropathy

Kidney & Blood Pressure Research, 2020
Objective: Co-deposition of mannose-binding lectin (MBL) and IgG4 anti-phospholipase A2 receptor (anti-PLA2R) autoantibodies under subepithelial cells has been observed in patients with idiopathic membranous nephropathy (iMN), but the relationships of ...
Ying Zhang, Yipeng Liu, Liming Liang, Liyan Liu, Xueqing Tang, Lijun Tang, Ping Chen, Juan Chen, Zunsong Wang, Wei Cao, Qinlan Chen, Na Zhao, Dongmei Xu   +12 more
doaj   +1 more source

A membranous nephropathy variant mimicking minimal change disease

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract This study characterizes a novel disease pattern of membranous nephropathy (MN) that exhibits overlapping clinicopathological features with minimal change disease (MCD), termed ‘MCD‐like MN’. Patients with histologically confirmed MN showing sparse and segmental subepithelial electron‐dense deposits (EDD) but clinically resembling MCD were ...
Chuqi Pan, Silin Xiang, Mengya Jiang, Yuan Li, Biao Huang, Tian Ye, Yuanyuan Du, Xuanli Tang, Yuan Yuan   +8 more
wiley   +1 more source

A study on the association between serum antiphospholipase A2 receptor antibodies and the hypercoagulable state in Chinese patients with primary membranous nephropathy

Renal Failure
Primary membranous nephropathy (PMN) increases venous thromboembolism (VTE) risk. This study investigated the relationship between anti-phospholipase A2 receptor (PLA2R) antibody status and coagulation profiles via thromboelastography (TEG) in PMN ...
Baolian Liu, Qiuyue Qin, Shuilin He
doaj   +1 more source

Always Consider a Repeat Kidney Biopsy: Acute Interstitial Nephritis Soon After Membranous Nephropathy

Case Reports in Nephrology, Volume 2026, Issue 1, 2026.
Introduction The heterogeneity of membranous nephropathy is well described in the literature, and its clinical course and response to treatment vary. Similarly, acute interstitial nephritis (AIN) can present in unexpected and unusual ways and should always be considered within the differential diagnosis of worsening renal function.
Jarrad Hopkins, James Nolan, Maleeka Ladhani, Chiang Lee, Poulami Jha   +4 more
wiley   +1 more source