Results 91 to 100 of about 2,423,946 (178)

A comparison of chemiluminescent immunoassay and enzyme-linked immunosorbent assay for detecting phospholipase A2 receptor antibody in primary membranous nephropathy

Practical Laboratory Medicine
Objective: The accurate detection of phospholipase A2 receptor (PLA2R) autoantibody is crucial in the diagnosis and monitoring of primary membranous nephropathy (pMN). While enzyme-linked immunosorbent assay (ELISA) is the commonly used detection method,
Xiaotao Ma, Ruiting Wang, Linting Wei, Pengfei Liu, Lanmei Jing, Jinghua Wang, Wei Dong, Xuefei Tian, Rongguo Fu   +8 more
doaj   +1 more source

Diagnostic specificity of autoantibodies to M-type phospholipase A2 receptor (PLA2R) in differentiating idiopathic membranous nephropathy (IMN) from secondary forms and other glomerular diseases

, 2017
Autoantibody against phospholipase A2 receptor (anti-PLA2R) is a sensitive and specific biomarker of idiopathic membranous nephropathy (iMN), being found in approximately 70% of iMN patients and only occasionally in other glomerular diseases.
Ravera, F., T. Stellato, G. Ortisi, Napodano, P, Ghiggeri, G., F. Ravera, Pregnolato, F., A. Volpi, F. Pregnolato, Stellato, T., B. Trezzi, G. Ghiggeri, G. Moroni, Radice, A., R. Brugnano, Pesce, G., V. Cantaluppi, D'Amico, M, Sinico, Renato A, Rolla, D., Londrino, F., F. Londrino, D. Rolla, M. E. Giovenzana, Rolla, D, Cantaluppi, V., Ghiggeri, G, M. D’Amico, G. Pesce, Rombolà, G, Pieruzzi, F., Trezzi, B., Napodano, P., Pieruzzi, F, Volpi, A., Brugnano, R, D’Amico, M., Moroni, G., Stellato, T, Pesce, G, Rombolà, G., Pregnolato, F, Brugnano, R., P. Napodano, Trezzi, B, Radice, A, Ravera, F, Ortisi, G, Londrino, F, Giovenzana, M. E., Giovenzana, M E, A. Radice, Cantaluppi, V, Ortisi, G., Sinico, Renato A., Renato A. Sinico, F. Pieruzzi, Volpi, A, Moroni, G, G. Rombolà   +59 more
core   +1 more source

The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery

Kidney International, 2019
The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary target in membranous nephropathy (MN) greatly advanced basic and clinical research. Primary MN is now considered a renal-limited autoimmune disease, with antibodies against PLA2R (aPLA2Rab) identified in 70-80 % of patients of various ethnic groups. Although the use of
van de Logt, A., van de Logt, A., Fresquet, M., Wetzels, J.F.M., Wetzels, J.F.M., Brenchley, P.   +5 more
openaire   +4 more sources

Anticorps anti-EPN et anti-PLA2R dans les glomérulopathies extramembraneuses: Le point en 2014

, 2015
Membranous nephropathy (MN) is the most common cause for nephrotic syndrome in adults and occurs as an idiopathic (primary) or secondary disease. Since the early 2000's, substantial advances have been made in the understanding of the molecular bases of ...
Broeders, Emine Nilufer, Nortier, Joëlle, Pozdzik, Agnieszka, Ronco, Pierre, Husson, Cécile, Rorive, Sandrine, Brochériou, Isabelle, Debiec, Hanna, Le Moine, Alain   +8 more
core  

Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cases

Renal Failure
Background This retrospective study aims to investigate the prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy (HBV-MN).Methods Clinicopathologic and serologic records of ...
Haitao Lu, Qianqian Xu, Guming Zou, Hongmei Gao, Yue Yang, Wenge Li, Li Zhuo   +6 more
doaj   +1 more source

Supplementary Material for: Serum Anti-PLA2R Antibody Predicts Treatment Outcome in Idiopathic Membranous Nephropathy

, 2016
Background: M-type phospholipase A2 receptor (PLA2R) has been identified as the major target antigen in idiopathic membranous nephropathy (IMN). However, the role of glomerular PLA2R (gPLA2R) and the associations of serum anti-PLA2R antibody (sPLA2R-Ab ...
Wang Y. (2884271), Cao Y. (3217773), Wang C. (2954256), Wei Q. (3217770), Wang Y.-X. (3217785), Diao T.-T. (3217782), Li J.-S. (3217776), Zhao S.-L. (3217767), Wei S.-Y. (3217788), Li B. (3217779), Qin Y. (3217764)   +10 more
core   +1 more source

Anti-phospholipase A2 receptor antibody and spontaneous remission in membranous nephropathy [PDF]

, 2018
Anti-phospholipase A2 receptor antibody; Membranous nephropathy; Spontaneous remissionAnticòs del receptor anti-fosfolipasa A2; Nefropatia membranosa; Remissió espontàniaAnticuerpo del receptor anti-fosfolipasa A2; Nefropatía membranosa; Remisión ...
Agraz Pamplona, Irene, Soler Romeo, Maria Jose, Diaz, Montserrat, Díaz Encarnación, Montserrat Mercedes, Universitat Autònoma de Barcelona, Soler, María José   +5 more
core   +1 more source

Cyclophosphamide induced early remission and was superior to rituximab in idiopathic membranous nephropathy patients with high anti-PLA2R antibody levels. [PDF]

BMC Nephrol, 2023
Xue C, Wang J, Pan J, Liang C, Zhou C, Wu J, Song S, Cui L, Zhang L, Liu Y, Dai B.   +10 more
europepmc   +1 more source

Advances in the pathogenesis and clinical applications of PLA2R-associated membranous nephropathy

Membranous nephropathy is one of the main pathological types of nephrotic syndrome. PLA2R（phospholipase A2 receptor）associated membranous nephropathy is the predominant type of primary membranous nephropathy， also known as idiopathic membranous ...
Sun Miao-xin, Zhao Xin-cheng, Li Zi-wei, Li Yun-xia, Chai Wen-xiu, Cai Pan-pan, Xin Ye, Duan Li-ping, Wu Hao-wen, Wang Ding-ding   +9 more
core   +1 more source

Glomerulonephrite extramembraneuse anti-PLA2R+: 39 ans d’activite sans insuffisance renale!

, 2019
Objectif: Rapporter un cas de Glomérulonéphrite extra membraneuse anti-PLA2R+ évoluant depuis 39 ans, sans insuffisance rénale. Observation : Le diagnostic histologique de syndrome néphrotique à lésions glomérulaires minimes fut posé en 1980 chez une ...
Djibril, M.A., Tsevi, Y.M., Aydin, S, Jadoul, M, Djagadou, K.A., Nemi, K.D.   +5 more
core   +1 more source