Results 51 to 60 of about 842,782 (192)
Review for QSAR studies and drug design of selected heterocyclic nucleus of antitubercular drugs
World Journal of Biology Pharmacy and Health SciencesThis review article explores the pressing issue of drug-resistant strains of Mycobacterium tuberculosis, which have emerged due to the widespread and uncontrolled use of antibiotics in clinical settings over several decades. In response to this challenge,
R. R. Jiyo +2 more
semanticscholar +1 more source
Ionophoric effects of the antitubercular drug bedaquiline
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Antibiotics generally target one of five essential cellular functions in bacteria, but many of these targets are now compromised through rapidly spreading antibiotic resistance.
Kiel Hards +6 more
semanticscholar +1 more source
Spina ventosa: An often missed diagnosis
Journal of Global Infectious Diseases, 2021 Rare and varied presentations of tuberculosis make it difficult for treating clinicians to arrive at the diagnosis. An adolescent female presented to the orthopedic outpatient department with slowly increasing swelling over the dorsum of the hand near ...
Ankur Agarwal +3 more
doaj +1 more source
Conservative management of tubercular intestinal obstruction with antitubercular drugs and steroid
Journal of Medical Science And clinical ResearchObjective: Tubercular intestinal obstruction is a challenging condition often necessitating surgical intervention. This case study aims to evaluate the effectiveness of conservative management, including antitubercular therapy, short-course steroids, and
Dr Jayesh Kalbhande
semanticscholar +1 more source
Cavitating Pulmonary Tuberculosis in a 3-year-old Child: A Case Report [PDF]
Indian Journal of Respiratory CareCavitating pulmonary tuberculosis (PTB) frequently occurs in adults and is uncommon in children. We report a case of a 3-year-old female child who presented with complaints of fever, cough, and poor weight gain.
Pushpa Kini +2 more
doaj +1 more source
Multiple Cutaneous Tuberculous Abscess: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2017 Cutaneous tuberculosis is a relatively rare form of extrapulmonary tuberculosis. It usually manifests secondary to haematogenous spread or from an underlying focus of infection. We report a case of multiple tuberculous abscesses without any primary focus.
Rahul Suna, Ramu Duttaluri
doaj +1 more source
Synthesis, Characterization, Theoretical Treatment and Antitubercular activity Evaluation of (E)-N’- (2,5-dimethoxylbenzylidene)nicotinohydrazide and some of its Transition Metal Complexes against Mycobacterium tuberculosis, H37Rv [PDF]
, 2016 (E)-N’-(2,5-dimethoxylbenzylidene)nicotinohydrazide) (HL) was synthesized by condensing nicotinic acid hydrazide and 2,5-dimethoxylbenzaldehyde with ONO coordination pattern.
Adekoya, J. A.
core +1 more source
Open ChemistryThe rising instances of drug resistance in Mycobacterium tuberculosis strains pose a significant global health challenge. Conventional tuberculosis (TB) treatments, which typically involve multiple antibiotics, face hurdles like drug resistance, reduced ...
Kirti Sharma +8 more
semanticscholar +1 more source
Microorganisms, 2023 Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), poses a global health challenge and is responsible for over a million deaths each year.
William M. Matern +8 more
doaj +1 more source
Chemistry &Biodiversity, EarlyView.Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall +9 more
wiley +1 more source