Results 121 to 130 of about 60,579 (143)
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MONOCLONAL ANTIBODY AGAINST HUMAN RENIN
The Journal of Clinical Endocrinology & Metabolism, 1981By spleen cell fusion with NS1 myeloma, a mouse hybridoma was obtained which secretes an antibody directed against human renin. This monoclonal antibody recognizes human and monkey renin, but neither hog nor mouse. Preliminary experiments demonstrate the potential of this antibody for renin immunopurification and characterization.
D, Simon +6 more
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Fully Human Therapeutic Monoclonal Antibodies
Journal of Immunotherapy, 2006Monoclonal antibody (mAb) therapy has been facilitated by a number of technologic advances over the past 30 years. Whereas hybridoma development of murine mAbs was requisite for the development of mAbs as drugs, the inherent immunogenicity of rodent sequences in humans has presented obstacles to the clinical application of mAbs.
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Monoclonal antibodies to human erythrocytes
European Journal of Immunology, 1982AbstractEight monoclonal antibodies from mouse hybridomas raised to normal human erythrocytes were tested with a panel of null‐type erythrocytes, enzyme‐treated normal cells, and by inhibition with human erythrocyte sialoglycoproteins. Two antibodies reacted poorly or not at all with RhNULL cells.
D J, Anstee, P A, Edwards
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Monoclonal Antibodies to Human Choriocarcinoma
American Journal of Reproductive Immunology and Microbiology, 1986ABSTRACT: We have established two monoclonal antibodies (TM7‐3 and TM3‐8) that react to choriocarcinoma cells. Both of these monoclonal antibodies have shown a similar reactive pattern to human cell lines, normal and neoplastic trophoblast tissues, and other fetal and adult tissues.
K, Yamashita +3 more
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A human monoclonal antibody to insulin
Diabetes, 1986To elucidate the immune aspects of insulin-dependent diabetes mellitus (IDDM), we attempted to generate human monoclonal anti-insulin antibodies by fusing peripheral blood lymphocytes obtained from 10 insulin-treated IDDM patients with cells from a human lymphoblastoid cell line. Hybridomas that secreted immunoglobulins appeared in 9 of 400 wells.
A, Livneh +5 more
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Human Monoclonal Antibody against Endotoxin
DICP, 1991Little progress has been made over the past several years in the treatment of gram-negative bacteremia and septic shock. Advances in biotechnology have led to the development of human monoclonal antibody against endotoxin (HA-1A), a toxic mediator of the septic response.
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Progress in clinical and biological research, 1989
J, Kan-Mitchell, M S, Mitchell
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J, Kan-Mitchell, M S, Mitchell
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