Lymphomatoid Papulosis Following Spesolimab Treatment for Generalised Pustular Psoriasis
Australasian Journal of Dermatology, EarlyView.
Mizuho Namba+6 more
wiley +1 more source
Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)
ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang+8 more
wiley +1 more source
Early caplacizumab and obinutuzumab enable successful treatment of relapsing thrombotic thrombocytopenic purpura without therapeutic plasma exchange: a case report. [PDF]
Schimpf J, Haller P, Zitt E.
europepmc +1 more source
Haemophilia Prophylaxis in the Age of Innovation: Exploring Opportunities for Personalized Treatment
ABSTRACT Introduction Recent advancements in haemophilia treatment have introduced a range of innovative therapies, including activated FVIII mimetics, ultra‐extended half‐life recombinant FVIII, rebalancing agents and gene therapy. These developments have transformed treatment options and expanded prophylaxis strategies.
Yesim Dargaud+5 more
wiley +1 more source
Structural Insights into the ADCC Mechanism and Resistance of Mogamulizumab, a First-in-Class Anti-CCR4 Therapy for Cutaneous T Cell Lymphoma. [PDF]
Choi SB+7 more
europepmc +1 more source
ABSTRACT Background Emicizumab is approved for routine prophylaxis, but limited data exist investigating the relationship between bleeds and exercise in people with haemophilia A (PwHA) receiving emicizumab. Aim To evaluate the relationship between physical activity and bleeding outcomes in Japanese PwHA receiving emicizumab prophylaxis.
Kagehiro Amano+11 more
wiley +1 more source
Passive Immunization in the Prevention and Treatment of Viral Infections. [PDF]
Moirangthem R, Bar-On Y.
europepmc +1 more source
Pharmacokinetics and safety of eptinezumab in children and adolescents with migraine
Abstract Objective The primary objective was to characterize the pharmacokinetics (PK) and safety of eptinezumab in children and adolescents with migraine. Background Migraine in children and adolescents is a prevalent and potentially debilitating disease, and few preventive therapies are approved for use in these populations. Eptinezumab, a calcitonin
Andrew D. Hershey+4 more
wiley +1 more source
The revolution in pharmacotherapy: from herbs to pills, moulds, antibodies to genetic tools. [PDF]
Lüscher TF.
europepmc +1 more source
Abstract Objectives/Background This study was undertaken to evaluate the postmarketing safety of monoclonal antibodies (mAbs) targeting the calcitonin gene‐related peptide pathway used for migraine prophylaxis through pharmacovigilance data analysis by examining suspected adverse events reported in Europe.
Victoria Nikitina+3 more
wiley +1 more source