Results 21 to 30 of about 394,452 (270)

The Immunoglobulins of Cold-Blooded Vertebrates [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Chen   +22 more
core   +2 more sources

Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

open access: yesCommunications Biology, 2022
The authors developed a methodology for bulk enrichment of antigen-specific B cells to improve the diversity of antibody sequences and increase the number of functional antigen-specific antibodies coming from different antibody generation platforms.
Ankit Mahendra   +20 more
doaj   +1 more source

Review of Immunoinformatic approaches to in-silico B-cell epitope prediction [PDF]

open access: yes, 2007
In this paper, the current state of in-silico, B-cell epitope prediction is discussed. Recommendations for improving some of the approaches encountered are outlined, along with the presentation of an entirely novel technique, which uses molecular ...
Rick Reitmaier
core   +2 more sources

Secondary Mechanisms of Affinity Maturation in the Human Antibody Repertoire

open access: yesFrontiers in Immunology, 2013
V(D)J recombination and somatic hypermutation (SHM) are the primary mechanisms for diversification of the human antibody repertoire. These mechanisms allow for rapid humoral immune responses to a wide range of pathogenic challenges.
Bryan S. Briney, James E. Crowe
doaj   +1 more source

Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development

open access: yesCell Reports, 2017
Antibody repertoire diversity and plasticity is crucial for broad protective immunity. Repertoires change in size and diversity across multiple B cell developmental stages and in response to antigen exposure.
Victor Greiff   +10 more
doaj   +1 more source

Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]

open access: yes, 2018
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A.   +8 more
core   +1 more source

Antibody Wars: Extreme Diversity [PDF]

open access: yesThe Journal of Immunology, 2006
People have pondered the Ab diversity problem for years as the universe of potential Ags was expanding relentlessly. Research showed that Abs could not only bind to pathogens such as bacteria, toxins, and viruses, but also to common proteins, like egg albumin, and synthetic chemical structures ...
openaire   +2 more sources

Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella [PDF]

open access: yes, 2017
Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens.
Banerjee, P S   +6 more
core   +1 more source

Antibody Repertoire: Embracing Diversity

open access: yesScience Translational Medicine, 2011
Adjuvanted formulations expand the vaccine-induced antibody repertoires against a virus and a parasite.
Pollard, A, Hill, A
openaire   +3 more sources

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