Results 11 to 20 of about 417,719 (249)
Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1
Cell Death and Disease, 2023 Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions ...
Huitong Bu +8 more
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ΔIK17 Antigen: A Possible Early Marker of Cancer Development
The International Journal of Biological Markers, 1996 ΔIK17 is a 44 kD molecule located on the surface of T, B and NK cells in normal peripheral blood mononuclear cells (PBMC) (1). The portion of PBMC expressing ΔIK17 was determined in 52 patients with benign breast diseases, 182 patients with breast ...
S. Perez +7 more
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The influence of acupuncture TENS currents on the proliferation of cancer cells tested in vitro
Rehabilitacja Medyczna, 2019 Introduction: Transcutaneous Electrical Nerve Stimulation (TENS) is a very popular, non-pharmacological antianalgetic method. Nonetheless, knowledge on using this method is very limited in the treatment of patients with cancer anamnesis.
Marzena Pełczyńska +3 more
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The recurrent laryngeal nerve and extralaryngeal branches in relation to the inferior thyroid artery, Berry’s ligament, tracheal groove, and Zuckerkandl tubercle: an experience of 60 thyroidectomies [PDF]
Folia MedicaAim: The aim of this study was to examine the anatomical variations of the inferior laryngeal nerve compared with its extralaryngeal branches, the inferior thyroid artery, Berry’s ligament, the tracheal groove, and the tubercle of Zuckerkandl, as ...
Zoi Nitsa +3 more
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Frontiers in Pharmacology, 2020 Repurposing of medicines has gained a lot of interest from the research community in recent years as it could offer safe, timely, and affordable new treatment options for cancer patients with high unmet needs.
Ciska Verbaanderd +5 more
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Experimental and Molecular Medicine, 2019 Cancer: How a plant metabolite analog suppresses tumor growth A synthetic analog of a chemical found in fruit suppresses tumor growth by targeting an RNA-binding protein (hnRNPA2B1) and preventing the production of a pro-cancer regulatory factor.
Nak-Kyun Soung +21 more
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Cells, 2018 Most cytotoxic agents have limited efficacy for solid cancers. Cell-cycle phase analysis at the single-cell level in solid tumors has shown that the majority of cancer cells in tumors is not cycling and is therefore resistant to cytotoxic chemotherapy ...
Shuya Yano, Robert M. Hoffman
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The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1
Cell & Bioscience, 2023 Background Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated.
Haojie Cheng +9 more
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A Novel Alkylating Agent, Glufosfamide, Enhances the Activity of Gemcitabine In Vitro, In Vivo
Neoplasia: An International Journal for Oncology Research, 2007 Glufosfamide is an alkylating agent consisting of iphosphoramide mustard conjugated to glucose that is currently included in clinical studies of pancreatic cancer.
W. Steve Ammons +4 more
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Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion
Biomedicines, 2022 Breast cancer has a high risk of recurrence and distant metastasis after remission. Controlling distant metastasis is important for reducing breast cancer mortality, but accomplishing this goal remains elusive.
Hee Yeon Kim +6 more
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