Results 91 to 100 of about 75,534 (305)
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
, 2014 IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
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Epilepsia, EarlyView.Abstract Objective Antiseizure medications are approved based on clinical trials that demonstrate their efficacy as measured by reductions in seizure frequency (SF). When designing these trials, trialists must select inclusion criteria where SF can be reliably measured to maintain statistical power.
Wesley T. Kerr +6 more
wiley +1 more source
Metabolic consequences of antiepileptic drugs [PDF]
, 2010 Purpose of Review: Chemical properties of the widely used older generation antiepileptic drugs (AEDs) suggest that they might be responsible for a number of medical comorbidities.
Mintzer, Scott
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Cleveland Clinic Journal of Medicine, 1989 In contrast with the situation only a decade ago, a profusion of new potential AEDs has been introduced for world-wide clinical testing. Which, if any, of these compounds will be added to the physician's armamentarium against epileptic seizures is unknown, but the continuing flow of testable compounds augurs well for the future.
openaire +2 more sources
Epilepsia, EarlyView.Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei +10 more
wiley +1 more source
Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence. [PDF]
, 2011 Two years after the warning issued by the Food and Drug Administration on an increased risk of suicide for people taking antiepileptic drugs (AEDs), a number of pharmacoepidemiologic studies have been published but the scientific community is far from ...
Hesdorffer, DC, Mula, M
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Optimal approach to standardized documentation in epilepsy clinics: A scoping review
Epilepsia, EarlyView.Abstract Clear documentation and transfer of information between health care providers is key to ensuring the delivery of high‐quality patient care. Our aim was to determine how to optimize and standardize physician documentation in outpatient epilepsy clinics as well as to highlight challenges and barriers to their implementation.
Shahab Marzoughi +8 more
wiley +1 more source
Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]
, 2010 Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert +3 more
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Seizure forecasting with epilepsy cycles: On the causality of forecasting pipelines
Epilepsia, EarlyView.Abstract Objective Seizure risk is modulated by multiscale brain rhythms. Previous studies using cycles in electroencephalography, heart rate, and wearable data suggest the possibility of forecasting seizures days in advance. However, they commonly rely on methods requiring (days of) information from time points beyond the moment of forecast (noncausal
Hongliu Yang +6 more
wiley +1 more source
Antiepileptic Drug Level Monitoring [PDF]
, 2008 Routine monitoring of antiepileptic drug levels does not alter seizure or side effect rates. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial [RCT] with less than 80 percent follow-up).
Malaty, Wail, Stigleman, Sue
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