Results 11 to 20 of about 75,534 (305)
Antiepileptic Drug Interactions [PDF]
Summary: This article reviews the potential interactions of antiepileptic drugs (AEDs) and the pharmacokinetic and pharmacodynamic principles involved. It describes the absorptive and distributive properties of AEDs and the effects on protein binding, hepatic metabolism, and elimination resulting from co‐administration of AEDs with food or other drugs.
J A, French, B E, Gidal
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Visual Disorders with Antiepileptic Drugs
Visual adverse effects induced by antiepileptic drugs (AED) are reviewed by researchers at the Departments of Pediatrics, Universities of Chieti and Bologna, Italy.
J Gordon Millichap
doaj +1 more source
Endocrine Function and Antiepileptic Drugs
The effects of valproate (VPA) in 40, carbamazepine (CBZ) in 19, and oxcarbazepine (OXC) in 18 girls with epilepsy on growth and maturation were compared to 49 healthy untreated controls examined at 8 to 18 years of age at the Departments of Neurology ...
J Gordon Millichap
doaj +1 more source
New insights into the mechanisms and sites of action of lamotrigine [PDF]
This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field excitatory postsynaptic potentials (fEPSP) and population spikes in the CA1 hippocampal region of guinea pigs.
Grunze, Heinz +3 more
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Therapeutic drug monitoring – antiepileptic drugs [PDF]
Aims To provide a brief critical review of the basis and contemporary practice of monitoring the concentrations of antiepileptic drugs in biological fluids. Methods The review is based on literature data and observations from clinical practice.
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Intravenous Antiepileptic Drugs in Russia
Launching four intravenous antiepileptic drugs: valproate (Depakene and Convulex), lacosamide (Vimpat), and levetiracetam (Keppra) – into the Russian market has significantly broadened the possibilities of rendering care to patients in seizure emergency ...
P. N. Vlasov
doaj +1 more source
Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]
Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y. +3 more
core +1 more source
Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]
Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M +6 more
core +1 more source
Teratogenic Potential of Antiepileptic Drugs
The effect of antiepileptic drugs on intrauterine growth is reviewed from the Center for Human Molecular Genetics, Nebraska, and the University of Newcastle upon Tyne, UK.
J Gordon Millichap
doaj +1 more source
Established antiepileptic drugs
Despite the recent entry into the market-place of a range of new pharmacological treatments for epilepsy, most patients still receive the standard antiepileptic drugs. This review considers the clinical place and practical use of these agents. Detailed consideration is given to carbamazepine, phenytoin, sodium valproate, phenobarbital and ethosuximide,
Brodie, Martin J., Dichter, Marc A.
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