New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
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Bulletin of the National Research Centre, 2021 Background Tea is an important plantation crop in India and world. Introduction of fertilisers and pesticides for better production polluted tea garden soils.
Sumedha Saha +3 more
doaj +1 more source
Extensive evolution of cereal ribosome-inactivating proteins translates into unique structural features, activation mechanisms, and physiological roles [PDF]
, 2017 Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
De Zaeytijd, Jeroen, Van Damme, Els
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Defining the frontiers between antifungal resistance, tolerance and the concept of persistence [PDF]
Drug Resistance Updates, 2015 A restricted number of antifungal agents are available for the therapy of fungal diseases. With the introduction of epidemiological cut-off values for each agent in important fungal pathogens based on the distribution of minimal inhibitory concentration (MIC), the distinction between wild type and drug-resistant populations has been facilitated ...
Delarze Eric, Sanglard Dominique
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Preclinical Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antifungal Activity of Liposomal Amphotericin B [PDF]
Clinical Infectious Diseases, 2019 The improved safety profile and antifungal efficacy of liposomal amphotericin B (LAmB) compared to conventional amphotericin B deoxycholate (DAmB) is due to several factors including, its chemical composition, rigorous manufacturing standards, and ability to target and transit through the fungal cell wall.
Adler-Moore J. +5 more
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Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]
, 2016 Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
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Microbiology Spectrum, 2021 The high morbidity and mortality of cryptococcal meningitis is due to the limited range of therapeutic options: only three classes of antifungal drugs are available (polyenes [amphotericin B], azoles [fluconazole], and pyrimidine analogues [flucytosine]).
Feng Yang +6 more
doaj +1 more source
Taxonomic study and partial characterization of antimicrobial compounds from a moderately halophilic strain of the genus Actinoalloteichus [PDF]
, 2011 A moderately halophilic actinomycete strain designated AH97 was isolated from a saline Saharan soil, and selected for its antimicrobial activities against bacteria and fungi.
Boudjelal, Farida +4 more
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Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans
Frontiers in Microbiology, 2020 Candida albicans is an important human pathogen and a major concern in intensive care units around the world. C. albicans infections are associated with a high mortality despite the use of antifungal treatments.
Eric Delarze +13 more
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Candida auris: a decade of understanding of an enigmatic pathogenic yeast [PDF]
, 2020 Candida auris is an enigmatic yeast that continues to stimulate interest within the mycology community due its rapid and simultaneous emergence of distinct clades.
Brown, Jason +4 more
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