Results 11 to 20 of about 497,334 (328)
Antigen Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs [PDF]
Frontiers in Immunology, 2016 Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterised by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Catherine Hughes +5 more
doaj +10 more sources
Reprogramming Cancer Cells to Antigen-presenting Cells [PDF]
Bio-Protocol, 2023 Cancer cells evade the immune system by downregulating antigen presentation. Although immune checkpoint inhibitors (ICI) and adoptive T-cell therapies revolutionized cancer treatment, their efficacy relies on the intrinsic immunogenicity of tumor cells ...
Alexandra Ferreira +5 more
doaj +5 more sources
Antigen-Presenting Cells in Psoriasis [PDF]
Life, 2022 Psoriasis is classically considered a chronic inflammatory skin disorder, however the identification of autoantigens in its pathogenesis established it as a T cell mediated autoimmune disease.
Dóra Antal +4 more
doaj +3 more sources
Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting Cells [PDF]
Cell Journal, 2023 Objective: Chimeric antigen receptor (CAR) T cell therapy has recently emerged as a promising approach for thetreatment of different types of cancer.
Ali Sayadmanesh +7 more
doaj +2 more sources
Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform [PDF]
Drug DeliveryDelivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy.
Barnabas Nyesiga +6 more
doaj +2 more sources
Role of B cells as antigen presenting cells
Frontiers in Immunology, 2022 B cells have been long studied for their role and function in the humoral immune system. Apart from generating antibodies and an antibody-mediated memory response against pathogens, B cells are also capable of generating cell-mediated immunity.
Ichwaku Rastogi +5 more
doaj +3 more sources
Frontiers in Immunology, 2023 BackgroundSepsis is a life-threatening condition with high mortality. A few studies have emerged utilizing single-cell RNA sequencing (scRNA-seq) to analyze gene expression at the single-cell resolution in sepsis, but a comprehensive high-resolution ...
Tuo Zhang +17 more
doaj +1 more source
Dendritic Cells: The Long and Evolving Road towards Successful Targetability in Cancer
Cells, 2022 Dendritic cells (DCs) are a unique myeloid cell lineage that play a central role in the priming of the adaptive immune response. As such, they are an attractive target for immune oncology based therapeutic approaches.
Enrica Marmonti +2 more
doaj +1 more source
CD47 Deficiency Ameliorates Ocular Autoimmune Inflammation
Frontiers in Immunology, 2021 Autoimmune uveitis is a sight-threatening ocular inflammatory condition in which the retina and uveal tissues become a target of autoreactive immune cells.
Yoko Okunuki +3 more
doaj +1 more source
Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]
Journal of Investigative Dermatology, 2000 Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Edward Miranda +8 more
openaire +3 more sources