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Antigen presentation to B cells [PDF]
B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers.
Harwood, Naomi E, Batista, Facundo D
openaire +2 more sources
The Antigen Presenting Cells Instruct Plasma Cell Differentiation
The professional antigen presenting cells (APCs), including many subsets of dendritic cells and macrophages, not only mediate prompt but nonspecific response against microbes, but also bridge the antigen-specific adaptive immune response through antigen ...
Wei eXu, Jacques eBanchereau
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Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells
Gold nanoparticles (AuNPs) have demonstrated outstanding performance in many biomedical applications. Their safety is recognised; however, their effects on the immune system remain ill defined. Antigen-presenting cells (APCs) are immune cells specialised
Arindam K. Dey +5 more
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Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials
The development of vaccines plays a vital role in the effective control of several fatal diseases. However, effective prophylactic and therapeutic vaccines have yet to be developed for completely curing deadly diseases, such as cancer, malaria, HIV, and ...
Veena Vijayan +3 more
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Role of B cells as antigen presenting cells
B cells have been long studied for their role and function in the humoral immune system. Apart from generating antibodies and an antibody-mediated memory response against pathogens, B cells are also capable of generating cell-mediated immunity.
Ichwaku Rastogi +5 more
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The aim of this study was to evaluate the level of secretion of IL-12β by mononuclear leukocytes of peripheral blood under infiltrative and disseminated pulmonary tuberculosis.
R. R. Khasanova +4 more
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Two Distinct Myeloid Subsets at the Term Human Fetal–Maternal Interface
During pregnancy, immune cells infiltrate the placenta at different stages of fetal development. NK cells and macrophages are the most predominant cell types.
Maria Laura Costa +12 more
doaj +1 more source
Human dendritic cell functional specialization in steady state and inflammation
Dendritic cells (DC) represent a heterogeneous population of antigen-presenting cells that are crucial in initiating and shaping immune responses. Although all DC are capable of antigen uptake, processing and presentation to T cells, DC subtypes differ ...
Arjan eBoltjes, Femke eVan Wijk
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Characterization of respiratory dendritic cells from equine lung tissues
Background Dendritic cells (DCs) are professional antigen-presenting cells that have multiple subpopulations with different phenotypes and immune functions. Previous research demonstrated that DCs have strong potential for anti-viral defense in the host.
Yao Lee +2 more
doaj +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source

