Characterisation of antigen-presenting cells in the murine female reproductive tract and its draining lymph nodes [PDF]
, 2011 Despite the global burden of sexually transmitted diseases, the immunology of the female reproductive tract is poorly understood. An understanding of how the distribution of antigen presenting cells in the tissue and cross talk between cell types both ...
Roche, Rebecca
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Microsomal membranes from antigen presenting cells present antigenic peptides to T cells: a novel approach in vaccine development. [PDF]
, 2010 PhDThe study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective vaccines are potent in generating neutralizing antibody responses.
Sofra, Vasiliki
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Tumor Antigen Presentation by Dermal Antigen-Presenting Cells [PDF]
Journal of Investigative Dermatology, 2000 Several phenotypes of antigen-presenting cells are present in the dermis, where they presumably function to present encountered antigens for immune responses. This study examined the ability of dermal antigen-presenting cells to present tumor-associated antigens for the induction of in vivo antitumor immunity.
Campton, Kristina +8 more
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Antigen presentation and T cell regulation by intestinal epithelial cells [PDF]
, 2022 Major histocompatibility complex (MHC) class II expression by intestinal epithelial cells (IECs) has been described in inflammatory bowel disease patients.
Heuberger, Cornelia
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Cancer Medicine, 2020 Background Daratumumab (Dara), an anti‐CD38 monoclonal antibody, has an immunologic mechanism of action through targeting of CD38 expressing immune cells in patients with multiple myeloma (MM). Furthermore, it was recently shown that CD38 upregulation in
Nicolas Stocker +6 more
doaj +1 more source
Microbiome, 2023 Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linked
Christina Farr Zuend +20 more
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The ABCs of Antigen Presentation by Stromal Non-Professional Antigen-Presenting Cells [PDF]
International Journal of Molecular Sciences, 2021 Professional antigen-presenting cells (APCs), such as dendritic cells and macrophages, are known for their ability to present exogenous antigens to T cells. However, many other cell types, including endothelial cells, fibroblasts, and lymph node stromal cells, are also capable of presenting exogenous antigens to either CD8+ or CD4+ T cells via cross ...
Tom J. Harryvan +3 more
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Recent Advances in Experimental Dendritic Cell Vaccines for Cancer
Frontiers in Oncology, 2021 The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies.
Ivan Y. Filin +4 more
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The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage [PDF]
, 2009 Objective: Trauma-hemorrhage results in depressed immune responses of antigen-presenting cells (APCs) and T-cells. Recent studies suggest a key role of depressed T-cell derived interferon (IFN)-g in this complex immune cell interaction.
Loehe, Florian +17 more
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Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells
Frontiers in Immunology, 2019 Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses.
Efrain Guzman +4 more
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