Results 21 to 30 of about 497,334 (328)

Antigen Presentation by Vascular Cells [PDF]

Frontiers in Immunology, 2017
Antigen presentation by cells of the vessel wall may initiate rapid and localized memory immune responses in peripheral tissues. Peptide antigens displayed on major histocompatibility complex (MHC) molecules on the surface of endothelial cells (ECs) can be recognized by T cell receptors on circulating effector memory T cells (TEM), triggering both ...
Rebecca Liu, Jordan S. Pober, Thomas D. Manes, Jonathan Merola   +3 more
openaire   +4 more sources

Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]

, 2014
Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham, Ahmadzadeh, Akbar, Anderson, Baine, Barber, Baur, Belkaid, Bensinger, Bergmann, Berzofsky, Blackburn, Brooks, Brooks, Brooks, Colonna, Das, Day, Duraiswamy, Ejrnaes, Frebel, Geijtenbeek, Guidotti, Ha, Jerome, Jung, Kasprowicz, Kaufmann, Kim, Klein, Kroemer, Kroy, Larsson, Liu, Lu, Maizels, Malek, Matsuzaki, Mier, Mumprecht, Nandedkar, Nurieva, Nurieva, Ramsay, Schietinger, Schwartz, Sofra, Soldaini, Steinman, Trautmann, Vezys, Waggoner, Wedemeyer, Wilson, Yi, Zhou   +55 more
core   +9 more sources

Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]

, 2020
Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core   +1 more source

Antigen presentation to B cells [PDF]

F1000 Biology Reports, 2010
B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers.
Facundo D. Batista, Naomi E. Harwood
openaire   +3 more sources

Daratumumab prevents programmed death ligand‐1 expression on antigen‐presenting cells in de novo multiple myeloma

Cancer Medicine, 2020
Background Daratumumab (Dara), an anti‐CD38 monoclonal antibody, has an immunologic mechanism of action through targeting of CD38 expressing immune cells in patients with multiple myeloma (MM). Furthermore, it was recently shown that CD38 upregulation in
Nicolas Stocker, Béatrice Gaugler, Laure Ricard, Frédéric deVassoigne, Zora Marjanovic, Mohamad Mohty, Florent Malard   +6 more
doaj   +1 more source

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer

Frontiers in Oncology, 2021
The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies.
Ivan Y. Filin, Kristina V. Kitaeva, Catrin S. Rutland, Albert A. Rizvanov, Valeriya V. Solovyeva   +4 more
doaj   +1 more source

Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Microbiome, 2023
Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linked
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener   +20 more
doaj   +1 more source

Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells

Frontiers in Immunology, 2019
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses.
Efrain Guzman, Myriam Pujol, Paolo Ribeca, Maria Montoya, Maria Montoya   +4 more
doaj   +1 more source

Lentinula Edodes Mycelia extract regulates the function of antigen-presenting cells to activate immune cells and prevent tumor-induced deterioration of immune function

BMC Complementary Medicine and Therapies, 2023
Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Lentinula Edodes
Shota Kajiyama, Takahiro Nagatake, Satoru Ishikawa, Koji Hosomi, Yuki Shimada, Yasunori Matsui, Jun Kunisawa   +6 more
doaj   +1 more source

Antigen presenting capacity of murine splenic myeloid cells [PDF]

, 2017
BACKGROUND: The spleen is an important site for hematopoiesis. It supports development of myeloid cells from bone marrow-derived precursors entering from blood. Myeloid subsets in spleen are not well characterised although dendritic cell (DC) subsets are
Hey, Ying-Ying, O'Neill, Helen C, Quah, Benjamin   +2 more
core   +2 more sources