Results 21 to 30 of about 2,473,811 (360)
Antigen presentation to B cells [PDF]
F1000 Biology Reports, 2010 B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers.
Facundo D. Batista, Naomi E. Harwood
openaire +3 more sources
Enhanced mechanical heterogeneity of cell collectives due to temporal fluctuations in cell elasticity [PDF]
Phys. Rev. E 107, 014401 (2023), 2022 Cells are dynamic systems characterized by temporal variations in biophysical properties such as stiffness and contractility. Recent studies show that the recruitment and release of actin filaments into and out of the cell cortex - a network of proteins underneath the cell membrane - leads to cell stiffening prior to division and softening immediately ...
arxiv +1 more source
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
Nature Communications, 2011 The immune synapse is an exquisitely evolved means of communication between T cells and antigen-presenting cells (APCs) during antigen recognition. Recent evidence points to the transfer of RNA via exosomes as a novel mode of intercellular communication.
M. Mittelbrunn +7 more
semanticscholar +1 more source
Bovine Derived in vitro Cultures Generate Heterogeneous Populations of Antigen Presenting Cells
Frontiers in Immunology, 2019 Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses.
Efrain Guzman +4 more
doaj +1 more source
Frontiers in Immunology, 2019 Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive immune responses.
S. Gaudino, Pawan Kumar
semanticscholar +1 more source
Emergence of collective propulsion through cell-cell adhesion [PDF]
Phys. Rev. E 97, 042413 (2018), 2017 The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell migration. The model consists of an amoeba cell with polarized cell-cell adhesion, which is controlled by
arxiv +1 more source
The ABCs of Antigen Presentation by Stromal Non-Professional Antigen-Presenting Cells [PDF]
International Journal of Molecular Sciences, 2021 Professional antigen-presenting cells (APCs), such as dendritic cells and macrophages, are known for their ability to present exogenous antigens to T cells. However, many other cell types, including endothelial cells, fibroblasts, and lymph node stromal cells, are also capable of presenting exogenous antigens to either CD8+ or CD4+ T cells via cross ...
Tom J. Harryvan +3 more
openaire +3 more sources
A cell membrane model that reproduces cortical flow-driven cell migration and collective movement [PDF]
, 2023 Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a cluster, referred to as cluster migration, are poorly understood.
arxiv +1 more source
Nature Communications, 2019 Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using exogenous antigens and adoptive cells, we show a concept of utilizing biologically reprogrammed cytomembranes of the fused cells (FCs) derived from dendritic ...
Wen-Long Liu +10 more
semanticscholar +1 more source
BMC Complementary Medicine and Therapies, 2023 Immune cell activation is essential for cancer rejection; however, the tumor microenvironment leads to deterioration of immune function, which enables cancer cells to survive and proliferate. We previously reported that oral ingestion of Lentinula Edodes
Shota Kajiyama +6 more
doaj +1 more source