Results 1 to 10 of about 48,519 (195)

The role of immunophenotyping in differential diagnosis of chronic lymphocytic leukemia [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Accurate diagnosis of chronic lymphocytic leukemia (CLL) acquires immunophenotyping by flow cytometry in order to facilitate differential diagnosis between CLL and other mature B-cell neoplasms (MBCN). Objective.
Dragović-Ivančević Tijana   +6 more
doaj   +3 more sources

Cure of a CD20-positive peripheral T-cell lymphoma-NOS with CHOPE regimen plus surgery a case report and literature review [PDF]

open access: yesFrontiers in Medicine
Peripheral T-cell lymphoma non-specific type (PTCL-NOS) is the most common subtype of mature T-cell tumors, which is clinically characterized by high invasiveness and poor prognosis.
Chenyu Chi   +4 more
doaj   +2 more sources

Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2017
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding ...
Dariush Shanehbandi   +6 more
doaj   +1 more source

Humoral Response to SARS-CoV-2 Antigen in Patients Treated with Monoclonal Anti-CD20 Antibodies: It Is Not All about B Cell Recovery

open access: yesNeurology International, 2022
Anti-CD20 therapies decrease the humoral response to SARS-CoV-2 immunization. We aimed to determine the extent of the humoral response to SARS-CoV-2 antigens in correlation with peripheral B-cell dynamics among patients with central nervous system ...
Julia Feige   +11 more
doaj   +1 more source

Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells

open access: yesJournal of Veterinary Medical Science, 2021
Chimeric antigen receptor (CAR) CAR-T cell therapy targeting CD20 can be a novel adoptive cell therapy for canine patients with B-cell malignancy. After injection of the CAR-T cells in vivo, monitoring circulating CAR-T cells is essential to prove in vivo persistence of CAR-T cells. In this study, we developed a novel monoclonal antibody against canine
SAKAI, Osamu   +4 more
openaire   +3 more sources

Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells

open access: yesFrontiers in Immunology, 2023
The activating receptor natural killer group 2, member D (NKG2D) represents an attractive target for immunotherapy as it exerts a crucial role in cancer immunosurveillance by regulating the activity of cytotoxic lymphocytes.
Sebastian Lutz   +19 more
doaj   +1 more source

Application of anti-CD20 monoclonal antibodies in the treatment of lymphoproliferative diseases [PDF]

open access: yesArchive of Oncology, 2009
Out of numerous studied monoclonal antibodies, only a few reached the stage of clinical application. The CD20 molecule, non-glycolysed phospholipoprotein (usually termed B1), belonging to the tetraspan (TM4SF) family, 35-37 kD, is characteristic for all ...
Pejčić Ivica, Vrbić Svetislav
doaj   +1 more source

Adaptive immunity in cancer immunology and therapeutics. [PDF]

open access: yes, 2014
Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,
Lockley, M, Spurrell, EL
core   +6 more sources

Rituximab Plus Chemotherapy Provides No Clinical Benefit in a Peripheral T-Cell Lymphoma not Otherwise Specified with Aberrant Expression of CD20 and CD79a: A Case Report and Review of the Literature

open access: yesDiagnostics, 2020
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common entity of mature T-cell neoplasms. PTCL-NOS generally has an aggressive behavior and is often refractory to standard therapy.
Alessandro Mangogna   +5 more
doaj   +1 more source

T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells [PDF]

open access: yesCancer Immunology Research, 2016
Abstract The adoptive transfer of T cells expressing anti-CD19 chimeric antigen receptors (CARs) has shown remarkable curative potential against advanced B-cell malignancies, but multiple trials have also reported patient relapses due to the emergence of CD19-negative leukemic cells.
Zah, Eugenia   +4 more
openaire   +4 more sources

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