CD20-positive peripheral T-cell lymphoma not otherwise specified: a case series and review of the literature [PDF]
Frontiers in OncologyPeripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is a heterogeneous and aggressive malignancy that usually lacks B-cell associated antigens.
Pan Zhou +8 more
doaj +2 more sources
Case Report: Bispecific CD20/CD30-targeted chimeric antigen receptor T-cell therapy for non-Hodgkin’s lymphoma [PDF]
Frontiers in ImmunologyCD19-directed CAR T-cell therapy is a breakthrough immunotherapy for B-cell malignancies. However, CD19 loss-mediated relapsed/refractory disease continues to pose a significant challenge, highlighting the urgent need for CAR T cells targeting ...
Yuejiao Huang +7 more
doaj +2 more sources
The role of immunophenotyping in differential diagnosis of chronic lymphocytic leukemia [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2014 Introduction. Accurate diagnosis of chronic lymphocytic leukemia (CLL) acquires immunophenotyping by flow cytometry in order to facilitate differential diagnosis between CLL and other mature B-cell neoplasms (MBCN). Objective.
Dragović-Ivančević Tijana +6 more
doaj +3 more sources
Neurology International, 2022 Anti-CD20 therapies decrease the humoral response to SARS-CoV-2 immunization. We aimed to determine the extent of the humoral response to SARS-CoV-2 antigens in correlation with peripheral B-cell dynamics among patients with central nervous system ...
Julia Feige +11 more
doaj +1 more source
Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding ...
Dariush Shanehbandi +6 more
doaj +1 more source
Frontiers in Immunology, 2023 The activating receptor natural killer group 2, member D (NKG2D) represents an attractive target for immunotherapy as it exerts a crucial role in cancer immunosurveillance by regulating the activity of cytotoxic lymphocytes.
Sebastian Lutz +19 more
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The Role of Innate APOBEC3G and Adaptive AID Immune Responses in HLA-HIV/SIV Immunized SHIV Infected Macaques [PDF]
, 2012 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Bartlett +62 more
core +13 more sources
Application of anti-CD20 monoclonal antibodies in the treatment of lymphoproliferative diseases [PDF]
Archive of Oncology, 2009 Out of numerous studied monoclonal antibodies, only a few reached the stage of clinical application. The CD20 molecule, non-glycolysed phospholipoprotein (usually termed B1), belonging to the tetraspan (TM4SF) family, 35-37 kD, is characteristic for all ...
Pejčić Ivica, Vrbić Svetislav
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Diagnostics, 2020 Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common entity of mature T-cell neoplasms. PTCL-NOS generally has an aggressive behavior and is often refractory to standard therapy.
Alessandro Mangogna +5 more
doaj +1 more source
Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis. [PDF]
, 1988 In patients with rheumatoid arthritis (RA), circulating CD5+ B lymphocytes, but not CD5- B lymphocytes, are increased in number and size, exist in an activated state, spontaneously proliferate, and secrete Ig that binds to the Fc fragment of IgG.
Burastero, SE +3 more
core +1 more source