Results 1 to 10 of about 139,688 (144)
Expression of the CD6 T lymphocyte differentiation antigen in normal human brain☆ [PDF]
Journal of Neuroimmunology, 1990 Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly.The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal humanbrain evidenced by immunohistochemistry and Northern blot analysis.
Mayer, Barbara +4 more
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B lymphocyte antigens in the differential diagnosis of human neoplasia [PDF]
Blood, 1978 Abstract Human B lymphocyte antigens (HBLA) were detected with fluorescent- labeled antibodies on malignant cells of 102 patients with Hodgkin disease and other lymphomas, plasma cell myeloma, and nonlymphoreticular neoplasms including carcinomas of the breast, lung, and ovary, soft tissue sarcomas, and neuroblastoma.
Marshall E. Kadin +3 more
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Acquisition of cytotoxic T lymphocyte-specific carbohydrate differentiation antigens. [PDF]
The Journal of experimental medicine, 1985 Cytotoxic T cell (CTL)-specific activation antigens, termed CT determinants, have been detected by monoclonal antibodies (mAb) that inhibit CTL function. At the cell surface, the CT antigens are associated with the T200 glycoproteins and two other proteins of Mr 140,000 and 85,000 and are present on a secreted protein, gp155.
Michael J. Bevan +3 more
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Incomplete Cd8+ T Lymphocyte Differentiation as a Mechanism for Subdominant Cytotoxic T Lymphocyte Responses to a Viral Antigen [PDF]
The Journal of Experimental Medicine, 2000 CD8+ cytotoxic T lymphocytes (CTLs) recognize antigen in the context of major histocompatibility complex (MHC) class I molecules. Class I epitopes have been classified as dominant or subdominant depending on the magnitude of the CTL response to the epitope.
Spencer, Juliet V, Braciale, Thomas J
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and phosphorylation of murine lymphocyte differentiation antigen CD5
Biochemical and Biophysical Research Communications, 1989 Ly-1, the murine lymphocyte differentiation antigen CD5, is phosphorylated constitutively in vivo. This phosphorylation is enhanced by phorbol 12-myristate 13-acetate (PMA) treatment, but not by concanavalin A, Ca2+ ionophore or dibutyryl cAMP. Prolonged PMA treatment abolished PMA-induced Ly-1 phosphorylation but not constitutive phosphorylation ...
Masatoshi Tagawa +2 more
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Structure and function of T lymphocyte differentiation antigens
Trends in Genetics, 1986 Abstract In addition to the T cell reception for antigen, T lymphocytes express a variety of additional T cell-specific surface molecules which are involved in recognition, activation and function. The structure, evolutionary relationship and functions of four of these T cell differentiation antigens are discussed.
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Modulation of T-lymphocyte differentiation antigens: potential relevance for multiple sclerosis. [PDF]
Proceedings of the National Academy of Sciences, 1982 Effects of the anti-T-cell monoclonal antibodies OKT3, OKT5, and OKT8 on T-cell surface properties and cell functions were evaluated. Incubation of mononuclear cells isolated from peripheral blood for 48 hr with each monoclonal antibody in the absence of complement resulted in modulation of their respective surface antigens; i.e., the number of cells ...
Barry G. W. Arnason +4 more
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Marine Life Science & Technology, 2022 AbstractCluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes and other cells associated with the immune system. Antibodies that react with CD antigens are known to be one of the most essential tools for identifying leukocyte subpopulations.
Tian, Hong-fei +5 more
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The role of SAP in antigen priming and differentiation of T lymphocytes
, 2015 Mutations in the SH2D1A gene that encodes signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) cause X-linked lymphoproliferative disease (XLP), a congenital immunodeficiency defined by exquisite sensitivity to Epstein-Barr virus (EBV).
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Recognition of a human T-lymphocyte differentiation antigen by an IgM monoclonal antibody.
Clinical and experimental immunology, 1982 A monoclonal antibody directed at a determinant on human T cells was produced and characterized. This IgM antibody, MBG6, bound to human peripheral blood T lymphocytes and to medullary thymocytes. It was unreactive with normal B cells, B-cell lines and granulocytes.
Bastin, J +4 more
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