Results 11 to 20 of about 199,223 (187)
Genetic deletion of Mst1 alters T cell function and protects against autoimmunity. [PDF]
Mammalian sterile 20-like kinase 1 (Mst1) is a MAPK kinase kinase kinase which is involved in a wide range of cellular responses, including apoptosis, lymphocyte adhesion and trafficking.
Konstantin V Salojin+24 more
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Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development. [PDF]
OBF1, also known as Bob.1 or OCA-B, is a B lymphocyte-specific transcription factor which coactivates Oct1 and Oct2 on B cell specific promoters. So far, the function of OBF1 has been mainly identified in late stage B cell populations. The central defect
Alain Bordon+7 more
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The Role of Adaptor Proteins in the Biology of Natural Killer T (NKT) Cells
Adaptor proteins contribute to the selection, differentiation and activation of natural killer T (NKT) cells, an innate(-like) lymphocyte population endowed with powerful immunomodulatory properties.
Evelyn Gerth, Jochen Mattner
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ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical ...
L. M. Karzakova
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Till yet there is no data concerning mechanisms of autoimmune diseases development. Experimental autoimmune encephalomyelitis (EAE) prone C57BL/6 (T- and B-lymphocyte response), non-autoimmune CBA, and Th mice with T cell response were immunized with ...
Kseniya S. Aulova+11 more
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Background Dendritic cells (DCs) are differentiated from monocytes, and have a strong ability to perform phagocytosis, present antigens and activate T cell immune response.
Chao-Ling Yao, Tsung-Yu Tseng
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Virus-specific cluster of differentiation 8 (CD8+) cytotoxic T cells (CTL) recognize viral antigens presented on major histocompatibility complex (MHC) class I chains on infected hepatocytes, with help from CD4+ T cells.
Hyosun Cho+3 more
semanticscholar +1 more source
Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells.
Mouldy Sioud+5 more
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B lymphocyte-induced maturation protein-1 (Blimp-1) serves as a master regulator of the development and function of antibody-producing B cells. Given that its function in T lymphocytes has been identified within the past decade, we review recent findings
Shin-Huei Fu+4 more
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Measles Vaccines Designed for Enhanced CD8+ T Cell Activation
Priming and activation of CD8+ T cell responses is crucial to achieve anti-viral and anti-tumor immunity. Live attenuated measles vaccine strains have been used successfully for immunization for decades and are currently investigated in trials of ...
Elena Busch+13 more
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