Results 11 to 20 of about 214,371 (284)

The Role of Adaptor Proteins in the Biology of Natural Killer T (NKT) Cells

Frontiers in Immunology, 2019
Adaptor proteins contribute to the selection, differentiation and activation of natural killer T (NKT) cells, an innate(-like) lymphocyte population endowed with powerful immunomodulatory properties.
Evelyn Gerth, Jochen Mattner
doaj   +1 more source

Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development. [PDF]

PLoS ONE, 2008
OBF1, also known as Bob.1 or OCA-B, is a B lymphocyte-specific transcription factor which coactivates Oct1 and Oct2 on B cell specific promoters. So far, the function of OBF1 has been mainly identified in late stage B cell populations. The central defect
Alain Bordon, Nabil Bosco, Camille Du Roure, Boris Bartholdy, Hubertus Kohler, Gabriele Matthias, Antonius G Rolink, Patrick Matthias   +7 more
doaj   +1 more source

ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS

Медицинская иммунология, 2014
. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical ...
L. M. Karzakova
doaj   +1 more source

Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine

Case Reports in Medicine, 2016
Indoleamine 2,3-dioxygenase (IDO) expression in dendritic cells (DCs) inhibits T-cell activation and promotes T-cell differentiation into regulatory T-cells.
Mouldy Sioud, Marta Nyakas, Stein Sæbøe-Larssen, Anne Mobergslien, Steinar Aamdal, Gunnar Kvalheim   +5 more
doaj   +1 more source

Production of Abzymes in Th, CBA, and C57BL/6 Mice before and after MOG Treatment: Comparing Changes in Cell Differentiation and Proliferation

Biomolecules, 2019
Till yet there is no data concerning mechanisms of autoimmune diseases development. Experimental autoimmune encephalomyelitis (EAE) prone C57BL/6 (T- and B-lymphocyte response), non-autoimmune CBA, and Th mice with T cell response were immunized with ...
Kseniya S. Aulova, Andrey E. Urusov, Ludmila B. Toporkova, Sergey E. Sedykh, Yuliya A. Shevchenko, Valery P. Tereshchenko, Sergei V. Sennikov, Thomas Budde, Sven G. Meuth, Nelly A. Popova, Irina A. Orlovskaya, Georgy A. Nevinsky   +11 more
doaj   +1 more source

Programmed Cell Death 1 (PD-1) and Cytotoxic T Lymphocyte-Associated Antigen 4 (CTLA-4) in Viral Hepatitis

International Journal of Molecular Sciences, 2017
Virus-specific cluster of differentiation 8 (CD8+) cytotoxic T cells (CTL) recognize viral antigens presented on major histocompatibility complex (MHC) class I chains on infected hepatocytes, with help from CD4+ T cells.
Hyosun Cho, Hyojeung Kang, H. H. Lee, C. Kim   +3 more
semanticscholar   +1 more source

Generation and Characterization of a Murine Monoclonal Antibody Specific for the Human T1-Cd5 Molecule

The International Journal of Biological Markers, 1987
Murine monoclonal antibodies (MoAbs) have found widespread applications in the characterization of the molecular and functional features of lymphocyte differentiation antigens.
Federico Genzano, Ada Funaro, Massimo Alessio, Lucia B. De Monte, Graziella Bellone, Licia Peruzzi, Manuela Zaccolo, Federico Caligari-Cappino, Fabio Malavasi   +8 more
doaj   +1 more source

New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function

Journal of Biomedical Science, 2017
B lymphocyte-induced maturation protein-1 (Blimp-1) serves as a master regulator of the development and function of antibody-producing B cells. Given that its function in T lymphocytes has been identified within the past decade, we review recent findings
Shin-Huei Fu, Li-Tzu Yeh, Chin-Chen Chu, B. Lin-Ju Yen, Huey-Kang Sytwu   +4 more
doaj   +1 more source

The synergistic and enhancive effects of IL-6 and M-CSF to expand and differentiate functional dendritic cells from human monocytes under serum-free condition

Journal of Biological Engineering, 2023
Background Dendritic cells (DCs) are differentiated from monocytes, and have a strong ability to perform phagocytosis, present antigens and activate T cell immune response.
Chao-Ling Yao, Tsung-Yu Tseng
doaj   +1 more source

Expression of the CD6 T lymphocyte differentiation antigen in normal human brain [PDF]

Journal of Neuroimmunology, 1990
Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly.The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal humanbrain evidenced by immunohistochemistry and Northern blot analysis.
Mayer, Barbara, Funke, Ilona, Seed, Brian, Riethmüller, Gert, Weiss, Elisabeth H.   +4 more
openaire   +3 more sources