Results 11 to 20 of about 17,759 (207)
Gemcitabine and pemetrexed are clinically approved antimetabolites for the therapy of mesothelioma diseases. These drugs are often applied in combination with platinum complexes and other drugs.
Bernhard Biersack
doaj +2 more sources
Risk of failing both methotrexate and mycophenolate mofetil from the First-line Antimetabolites as Steroid-sparing Treatment (FAST) uveitis trial [PDF]
Background The antimetabolites methotrexate (MTX) and mycophenolate mofetil (MMF) are commonly used as initial corticosteroid-sparing treatment for uveitis. There is little data examining risk factors for failing both MTX and MMF.
Amit K. Reddy +15 more
doaj +2 more sources
Steroidal Antimetabolites Protect Mice against Trypanosoma brucei
Trypanosoma brucei, the causative agent for human African trypanosomiasis, is an emerging ergosterol-dependent parasite that produces chokepoint enzymes, sterol methyltransferases (SMT), not synthesized in their animal hosts that can regulate cell ...
Minu Chaudhuri +4 more
doaj +2 more sources
Long-term follow-up of trabeculectomy without antimetabolites in patients with uveitis
To determine the long-term success rate after trabeculectomy without antimetabolites in patients with ...
Stavrou, P, Murray, P I; id_orcid
core +6 more sources
Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists [PDF]
AIMS: To investigate whether drugs others than mycophenolic acid and ipilimumab might cause graft-versus-host-like apoptotic enteropathy, the clinicopathological findings in four patients were examined who had developed watery diarrhoea and apoptotic ...
Rogler, Gerhard +6 more
core +2 more sources
Cancer and viral infections continue to threaten humankind causing death worldwide. Hence, the discovery of new anticancer and antiviral agents still represents a major scientific goal.
Roberta Ibba +10 more
doaj +1 more source
Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations.
Małgorzata Milczarek +7 more
doaj +1 more source
By December 2019, humanity was challenged by a new infectious respiratory disease named coronavirus disease of 2019 or COVID-19. This is a viral infection based on the presence of the previously non-problematic coronavirus with assigned number 2.
Faiha M. Al-Ardhi +3 more
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source

