Results 21 to 30 of about 17,759 (207)
The article describes modern approaches to controlling wound healing after fistulizing glaucoma surgery. It provides a classification of refractory glaucoma degrees and summarizes risk factors for excessive scarring. Author describes various applications
S. Yu. Petrov
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Antimetabolites as an adjunct to dacryocystorhinostomy for nasolacrimal duct obstruction [PDF]
Background: Nasolacrimal duct obstruction (NLDO) is a condition that results in the overflow of tears (epiphora) or infection of the nasolacrimal sac (dacryocystitis).
Dinesh Selva +9 more
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Genome‐scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype–phenotype relationship in a mechanistic manner.
Rasmus Agren +5 more
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Cancer Metabolism and Drug Resistance
Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is ...
Mahbuba Rahman, Mohammad Rubayet Hasan
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Variation of Cost among Anti-cancer Drugs Available in Indian Market [PDF]
Introduction: Although cancer remains a major health problem all over the world, its treatment is limited by affordability of patients in a developing country like India.
Bhanu Prakash Kolasani +2 more
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New Steroidal Selenides as Proapoptotic Factors
Cytostatic and pro-apoptotic effects of selenium steroid derivatives against HeLa cells were determined. The highest cytostatic activity was shown by derivative 4 (GI50 25.0 µM, almost complete growth inhibition after three days of culture, and over 97 ...
Izabella Jastrzebska +7 more
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Xeloda as first-line therapy of metastatic colorectal cancer-our experience [PDF]
BACKGROUND: Results of phase III clinical studies comparing efficacy of Xeloda vs. standard 5-FU/FA protocols as first line therapy of metastatic colorectal carcinoma (MCRC), have shown better efficacy of Xeloda, with less toxic adverse effects, apart ...
Kovčin Vladimir +4 more
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Cationic antimicrobial peptides (AMPs) are active immune effectors of multicellular organisms and are also considered as new antimicrobial drug candidates.
Alexandro Rodríguez-Rojas +8 more
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Adenosine kinase of Trypanosoma brucei and its role in susceptibility to adenosine antimetabolites
Trypanosoma brucei cannot synthesize purines de novo and relies on purine salvage from its hosts to build nucleic acids. With adenosine being a preferred purine source of bloodstream-form trypanosomes, adenosine kinase (AK; EC 2.7.1.20) is likely to be a
Önal, Pinar +3 more
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BackgroundPemetrexed and gemcitabine are both antimetabolites drugs approved in advanced non-small cell lung cancer (NSCLC). Their toxicity profile is well known. However, rare vascular side effects can occur such as vascular acrosyndromes and especially
Margaux Geier +6 more
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