Results 31 to 40 of about 25,615 (222)

Isolation and identification of Bacillus strains with antimycobacterial activity [PDF]

open access: yes, 2011
Tuberculosis is the principal cause of death worldwide due to an infectious disease. The resurgence of tuberculosis, followed by the increase in prevalence of infections caused by nontuberculous mycobacteria (NTM), as well as the multi-drug resistance ...
Abdellah, Houari   +6 more
core   +1 more source

Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity

open access: yesPharmaceuticals, 2022
Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB), the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug has seriously decreased due to emerging INH-resistant strains of ...
Ebru Koçak Aslan   +9 more
doaj   +1 more source

Antimycobacterial and cytotoxicity activities of free and liposome-encapsulated 3-(4'-bromo[1,1'-biphenyl-4-yl)-3-(4-bromo-phenyl)-N,N-dimethyl-2-propen-1-amine [PDF]

open access: yes, 2010
The antimycobacterial activity of 3-(4'-bromo[1,1'-biphenyl-4-yl)-3-(4-bromo-phenyl)-N,N-dimethyl-2-propen-1-amine (BBAP), free or incorporated in preformed liposomes, on extracellular M.
ANDRADE-SANTANA, Maria H.   +3 more
core   +2 more sources

N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers

open access: yesMolecules, 2020
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb), each year causing millions of deaths. In this article, we present the synthesis and biological evaluations of new potential antimycobacterial compounds containing a ...
Martin Juhás   +12 more
doaj   +1 more source

Investigating the Antituberculosis Activity of Selected Commercial Essential Oils and Identification of Active Constituents Using a Biochemometrics Approach and In Silico Modeling

open access: yesAntibiotics, 2022
Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis which has become prevalent due to the emergence of resistant M. tuberculosis strains.
Katyna J. Boussamba-Digombou   +6 more
doaj   +1 more source

Antiprotozoal and antimycobacterial activities of Persea americana seeds [PDF]

open access: yes, 2013
BACKGROUND: Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.
Adelina Jiménez-Arellanes   +5 more
core   +1 more source

New Small-Molecule Synthetic Antimycobacterials [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2005
Drugs for treating tuberculosis (TB) have been available for over half a century, and yet the incidence of disease worldwide continues to rise year by year. In 2002, the last year for which statistics are available, it is estimated that 24,000 people developed active disease and close to 5 ...
Ballell, Lluis   +3 more
openaire   +5 more sources

Therapeutic Potential of Silver Nanoparticles (AgNPs) as an Antimycobacterial Agent: A Comprehensive Review

open access: yesAntibiotics
The uncontrolled emergence of multidrug-resistant mycobacterial strains presents as the primary determinant of the present crisis in antimycobacterial therapeutics and underscores tuberculosis (TB) as a daunting global health concern.
Nilakshi Barua, Alak Kumar Buragohain
doaj   +1 more source

Synthesis, in-vitro antimicrobial and antitubercular screening of Schiff bases of 3-amino-1-phenyl-4- [2-(4-phenyl-1,3-thiazol-2-yl) hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-one

open access: yesJournal of Pharmacy and Bioallied Sciences, 2013
Purpose: Synthesis and antimicrobial activity of some Schiff bases of 3-amino-1-phenyl-4- [2-(4-phenyl-1,3-thiazol-2-yl) hydrazin-1-ylidene]-4,5-dihydro-1H-pyrazol-5-ones (TZP4a-l) are described.
K K Sivakumar, A Rajasekaran
doaj   +1 more source

Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities : compounds modified in the imidazole ring [PDF]

open access: yes, 2010
Purine analogs modified in the five-membered ring have been synthesized and examined for antibacterial activity against Mycobacterium tuberculosis H37Rv in vitro employing the microplate alamar blue assay (MABA). The 9-deaza analogs were only found to be
Charnock, Colin   +5 more
core   +2 more sources

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