C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol [PDF]
Frontiers in Antibiotics, 2023 IntroductionThe emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease which remains one of the leading infectious causes of death worldwide.
Liam T. Martin +9 more
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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis [PDF]
Advances in Pharmacological and Pharmaceutical Sciences, 2021 Mycobacterium tuberculosis has developed extensive resistance to numerous antimycobacterial agents used in the treatment of tuberculosis. Insufficient intracellular accumulation of active moieties allows for selective survival of mycobacteria with drug ...
Erika Kapp +8 more
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Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound [PDF]
Scientia Pharmaceutica, 2017 Twelve N-substituted-glycinyl triazolyl oxazolidinone derivatives were screened for antimycobacterial activity against susceptible (Mycobacterium tuberculosis (Mtb) H37Rv) and resistant (isoniazid (INH)-resistant Mtb (SRI 1369), rifampin (RMP)-resistant ...
Naser F. Al-Tannak, Oludotun A. Phillips
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Fractions and isolated compounds from Oxyanthus speciosus subsp. stenocarpus (Rubiaceae) have promising antimycobacterial and intracellular activity [PDF]
BMC Complementary and Alternative Medicine, 2019 Background Tuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global practice for the treatment and prevention of diverse ailments including tuberculosis.
Abimbola O. Aro +5 more
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Antiprotozoal and antimycobacterial activities of Persea americana seeds [PDF]
, 2013 BACKGROUND: Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.
María Adelina Jiménez-Arellanes +5 more
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Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles [PDF]
Frontiers in Chemistry, 2020 The appearance of drug-resistant strains of Mycobacterium tuberculosis and the dramatic increase in infection rates worldwide evidences the urgency of developing new and effective compounds for treating tuberculosis. Benzimidazoles represent one possible
Rogelio Jiménez-Juárez +11 more
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International Journal of MycobacteriologyBackground: Tuberculosis (TB) caused by Mycobacterium tuberculosis complex remains a leading cause of morbidity and mortality worldwide. The zoonotic infectious condition represents a never-ending challenge toward which drug discovery efforts are needed.
Joseph Mwanzia Nguta
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Improved antimycobacterial activity of rifampin using solid lipid nanoparticles [PDF]
, 2012 Ehsan Aboutaleb +6 more
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Assessment of antimycobacterial activities of pure compounds extracted from Thai medicinal plants against clarithromycin-resistant Mycobacterium abscessus [PDF]
PeerJ, 2021 Background Infection with Mycobacterium abscessus is usually chronic and is associated with clarithromycin resistance. Increasing drug resistance is a major public-health problem and has led to the search for new antimycobacterial agents.
Auttawit Sirichoat +6 more
doaj +2 more sources
Draft Genome Sequences of Three Sponge-Associated Actinomycetes Exhibiting Antimycobacterial Activity. [PDF]
Microbiol Resour Announc, 2019 Tizabi D, Sosa A, Bachvaroff T, Hill RT.
europepmc +2 more sources