Results 11 to 20 of about 21,202 (267)

Antimycobacterial Activity of Salicylanilide Benzenesulfonates [PDF]

open access: yesMolecules, 2012
A series of eighteen novel esters of salicylanilides with benzenesulfonic acid were designed, synthesized and characterized by IR, 1H-NMR and 13C-NMR. They were evaluated in vitro as potential antimycobacterial agents towards Mycobacterium tuberculosis ...
Jiřina Stolaříková   +3 more
doaj   +3 more sources

N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity [PDF]

open access: yesMolecules, 2016
A series of nineteen N-(alkoxyphenyl)-2-hydroxynaphthalene-1-carboxamides and a series of their nineteen positional isomers N-(alkoxyphenyl)-1-hydroxynaphthalene-2-carboxamides were prepared and characterized.
Tomas Gonec   +10 more
doaj   +3 more sources

Antimycobacterial and cytotoxicity activity of microcystins [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu1] microcystin-LR. Methods The antimicrobial activity of M. aeruginosa extract
Daniela Fernandes Ramos   +6 more
doaj   +4 more sources

Bis dihydropyrimidine: synthesis and antimycobacterial activity [PDF]

open access: bronzeJournal of Enzyme Inhibition and Medicinal Chemistry, 2010
A series of bis dihydropyrimidine compounds were synthesised by reacting dapsone with acetylacetoacetate to produce N1-4-[4-(2-oxopropylcarboxamido) phenylsulphonyl] phenyl-3-oxobutanamide, then treated with guanidine hydrochloride and an appropriate aldehyde with a catalytic amount of p-toluene sulphonic acid (PTSA) in the presence of methanol to ...
Mohamed Ashraf Ali   +4 more
openalex   +3 more sources

Prospects for Adding Drugs with Known Anti-tuberculosis Activity to the Composition of Bone Cement for Treatment of Tuberculous Arthritis

open access: yesТуберкулез и болезни лёгких, 2022
The objective: to evaluate the possibility of using linezolid, amikacin, levofloxacin and bedaquiline mixed with bone cement for the treatment of patients with tuberculous arthritis taking into account changes in mechanical properties of bone cement ...
E. O. Peretsmanas   +5 more
doaj   +1 more source

Antimycobacterial activities of riminophenazines [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1999
Riminophenazines were specifically developed as drugs active against Mycobacterium tuberculosis but extensive research over several decades has shown that these compounds are also active against many other mycobacterial infections, particularly those caused by Mycobacterium leprae and the Mycobacterium avium complex (MAC).
V M, Reddy   +2 more
openaire   +2 more sources

Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): This study explored Indonesian Actinobacteria which were isolated from Curcuma zedoaria endophytic microbes and mangrove ecosystem for new antimycobacterial compounds.
Maya Rakhmawatie   +5 more
doaj   +1 more source

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents

open access: yesMolecules, 2021
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year.
Negar Maafi   +14 more
doaj   +1 more source

Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis

open access: yesMicrobiology Spectrum, 2023
Shorter and more effective treatment regimens as well as new drugs are urgent priorities for reducing the immense global burden of tuberculosis (TB). As treatment of TB currently requires multiple antibiotics with diverse mechanisms of action, any new ...
Rachel F. Rollo   +7 more
doaj   +1 more source

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