Results 61 to 70 of about 21,202 (267)

Anti-mycobacterial activity of polyketides from Penicillium sp. endophyte isolated from Garcinia nobilis against Mycobacterium smegmatis

International Journal of Mycobacteriology, 2016
Objective/background: According to estimates by the World Health Organization, there were 9.6 million new tuberculosis (TB) cases in 2014: 5.4 million among men, 3.2 million among women, and 1.0 million among children.
Jean Bosco Jouda, Isabelle Kamga Mawabo, Augustin Notedji, Céline Djama Mbazoa, Jean Nkenfou, Jean Wandji, Céline Nguefeu Nkenfou   +6 more
doaj   +1 more source

Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Ocotea notata from Brazilian Restinga

The Scientific World Journal, 2015
The genus Ocotea (Lauraceae) is distributed mainly in tropical and subtropical regions. Some species of this genus as O. puberula and O. quixos have been described in the literature, showing antibacterial activity.
Isabela Francisca Borges Costa, Sanderson Dias Calixto, Marlon Heggdorne de Araujo, Tatiana Ungaretti Paleo Konno, Luzineide Wanderley Tinoco, Denise Oliveira Guimarães, Elena B. Lasunskaia, Ivana Ramos Correa Leal, Michelle Frazão Muzitano   +8 more
doaj   +1 more source

Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]

, 2017
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang), Kaneko, T. (Takushi), Nuryastuti, T. (Titik), Ritmaleni, R. (Ritmaleni), Wahyuningrum, R. (Retno), Wahyuono, S. (Subagus)   +5 more
core  

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

CD23 Mediates Antimycobacterial Activity of Human Macrophages [PDF]

Infection and Immunity, 2009
ABSTRACTEngagement of surface receptors contributes to the antimicrobial activity of human immune cells. We show here that infection of human monocyte-derived macrophages (MDM) with liveMycobacterium aviuminduced the expression of CD23 on their membrane.
M Djavad, Mossalayi, Ioannis, Vouldoukis, Maria, Mamani-Matsuda, Tina, Kauss, Jean, Guillon, Jeanne, Maugein, Daniel, Moynet, Jérôme, Rambert, Vanessa, Desplat, Dominique, Mazier, Philippe, Vincendeau, Denis, Malvy   +11 more
openaire   +2 more sources

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

In Vitro Antimycobacterial Activities of Capuramycin Analogues [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT Translocase I inhibitor compounds derived from capuramycin demonstrated rapid bactericidal activity against several different mycobacterial species. SQ641 was the most active of the compounds, with a MIC of 0.12 to 8 μg/ml, a postantibiotic effect of 55 h, and interesting synergistic effects with other antitubercular drugs.
Venkata M, Reddy, Leo, Einck, Carol A, Nacy   +2 more
openaire   +2 more sources

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Structural Simplification of Bedaquiline: the Discovery of 3-(4-(N,N-dimethylaminomethyl)phenyl)quinoline Derived Antitubercular Lead Compounds [PDF]

, 2016
Bedaquiline (BDQ) is a novel and highly potent last-line antituberculosis drug that was approved by the US FDA in 2013. Owing to its stereo-structural complexity, chemical synthesis and compound optimization are rather difficult and expensive. This study
Cui, HC, Fu, LF, He, CH, Meier, TK, Preiss, LP, Wang, BW, Wen, HW, Yin, DY, Zhang, XZ   +8 more
core   +1 more source

Antimycobacterial Activity of Some Turkish Plants

Pharmaceutical Biology, 2004
In this study, 70% ethanol extracts from 98 different plant species distributed among 21 families were evaluated for antimycobacterial activity. Sempervirine was isolated from Buxus sempervirens with a minimum inhibitory concentration (MIC) of 6.25 µg/ml.
Palittapongarnpim, P, Sener, B, Kizilay, CA, Tosun, F, Vural, M   +4 more
openaire   +2 more sources