Results 231 to 240 of about 3,605,716 (385)

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo‐Resistant Patient‐derived Glioblastoma Cells

Advanced Science, EarlyView.
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh, Amir Seyfoori, Shahla Shojaei, Sarah Lane, Tian Zhao, Mahdieh Shokrollahi Barough, Julian J. Lum, Patrick Walter, Mohsen Akbari   +8 more
wiley   +1 more source

Effects of lipopolysaccharide administration on thymus damage, antioxidant capacity and immune function in weaned piglets. [PDF]

J Vet Res
Bai L, Jiang Y, Li X, Yu W, Zhu W, Zhao G, Yang T, Zhou Y, Li J, Li Y.   +9 more
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Study on the Extraction Technology and Antioxidant Capacity of Rhodymenia intricata Polysaccharides. [PDF]

Foods
Dong S, Wu Y, Luo Y, Lv W, Chen S, Wang N, Meng M, Liao K, Yang Y.   +8 more
europepmc   +1 more source

The effect of one year swimming exercise on oxidant stress and antioxidant capacity in aged rats.

, 2004
F Gündüz, ÜK Şentürk, O Kuru, B Aktekin, MR Aktekin   +4 more
openalex   +1 more source

Anthocyanin-rich purple potato flake extract has antioxidant capacity and improves antioxidant potential in rats [PDF]

, 2006
Kyu‐Ho Han, Mitsuo Sekikawa, Ken‐ichiro Shimada, Makoto Hashimoto, Naoto Hashimoto, Takahiro Noda, H. Tanaka, Michihiro Fukushima   +7 more
openalex   +1 more source

Anticoagulant Effects of Antioxidant Capacity [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1996
Gary Thorpe, S. R. J. Maxwell, D J Maslin, C A Rea, H. Thomason   +4 more
openaire   +2 more sources

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Effects of Lysophospholipids on the Antioxidant Capacity, Digestive Performance, and Intestinal Microbiota of Litopenaeus vannamei. [PDF]

Biology (Basel)
Yan H, Wang Y, Liang H, Duan Y, Wang J, Zhou C, Huang Z.   +6 more
europepmc   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

Advanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li, Liwen Huang, Chenxiao Guo, Jing Ren, Xi Chen, Yachu Ke, Zengyu Xun, Wenzhuo Hu, Yilin Qi, Heping Wang, Zhongying Gong, Xing‐Jie Liang, Xue Xue   +12 more
wiley   +1 more source