Antioxidant activity of the thioredoxin system
The thioredoxin system is composed of thioredoxin (Trx), thioredoxin reductase (TR) and reduced nicotinamide adenine dinucleotide phosphate. Trx is an important antioxidant molecule that can resist cell death caused by various stresses and plays a prominent role in redox reactions.
openaire +2 more sources
Oxidative Stress and Antioxidant System in Periodontitis [PDF]
Periodontitis is a common inflammatory disease, which is initiated by bacterial infection and subsequently progressed by aberrant host response. It can result in the destruction of teeth supporting tissues and have an influence on systemic health.
Yue Wang+3 more
openaire +4 more sources
Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey+39 more
core +2 more sources
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A.+6 more
core +1 more source
Low energy electron interactions with resveratrol and resorcinol: anion states and likely dissociation pathways [PDF]
We report a computational study of the anion states of the resveratrol (RV) and resorcinol (RS) molecules, also investigating dissociative electron attachment (DEA) pathways. RV has well known beneficial effects in human health, and its antioxidant activity was previously associated with DEA reactions producing H$_2$.
arxiv +1 more source
Application of Molecular Topology to the Prediction of Antioxidant Activity in a Group of Phenolic Compounds [PDF]
The study of compounds with antioxidant capabilities is of great interest to the scientific community, as it has implications in several areas, from Agricultural Sciences to Biological Sciences, including Food Engineering, Medicine and Pharmacy.
arxiv
Distributed Reinforcement Learning for Molecular Design: Antioxidant case [PDF]
Deep reinforcement learning has successfully been applied for molecular discovery as shown by the Molecule Deep Q-network (MolDQN) algorithm. This algorithm has challenges when applied to optimizing new molecules: training such a model is limited in terms of scalability to larger datasets and the trained model cannot be generalized to different ...
arxiv
Improving cold atmospheric pressure plasma efficacy on breast cancer cells control-ability and mortality by using vitamin C and static magnetic field [PDF]
Since the last decades, there have been numerous reports about the interaction of magnetic field (MF) and cold atmospheric plasma (CAP) with the biological systems, separately. In this manuscript, we have investigated the combined effect of CAP with the static magnetic field (SMF) as an effective method for cancer cells treatment.
arxiv +1 more source
Antioxidant Peptidomics Reveals Novel Skin Antioxidant System
It is generally agreed that reactive oxygen species (ROS) contribute to skin aging, skin disorders, and skin diseases. Skin possesses an extremely efficient antioxidant system. This antioxidant activity is conferred by two systems: antioxidant enzymes and small molecules that can scavenge ROS by donating electrons.
Xu Wang+13 more
openaire +3 more sources
Herbal Remedies for Combating Irradiation: a Green Antiirradiation Approach [PDF]
Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane.
Choong, Y. S.+8 more
core +1 more source