Results 11 to 20 of about 162,577 (262)
Backbone modified TBA analogues endowed with antiproliferative activity [PDF]
Background: Thrombin binding aptamer (TBA) is endowed with antiproliferative properties but its potential development is counteracted by concomitant anticoagulant activity. Methods: Five oligonucleotides (ODNs) based on TBA sequence (GGTTGGTGTGGTTGG) and
AMATO, TERESA +8 more
core +1 more source
Antiproliferative activity of spinasterol isolated of Stegnosperma halimifolium (Benth, 1844)
Cancer is the major cause of death in the world, representing a significant public health problem. Plants have been shown as a great source of secondary metabolites with anticancer activity.
Salvador Enrique Meneses-Sagrero +5 more
doaj +1 more source
The fruit of Tetradium ruticarpum (TR) is commonly used in Chinese herbal medicine and it has known antiproliferative and antitumor activities, which can serve as a good source of functional ingredients.
Chun-Han Su +9 more
doaj +1 more source
Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani +11 more
core +2 more sources
Antiproliferative Activity of Greek Propolis
The butanolic extract and the isolated chemical constituents, mainly diterpenes and flavonoids, from Greek propolis have been tested for their cytostatic activities against human malignant and normal cell strains. The extract and the diterpenes were found to be the most active against HT-29 human colon adenocarcinoma cells, without affecting normal ...
Pratsinis, H. +3 more
openaire +3 more sources
Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity
Oligonucleotides with an antiproliferative activity for human cancer cells have attracted attention over the past decades; many of them have a G-quadruplex structure (GQ), and a cryptic target.
Olga Antipova +6 more
doaj +1 more source
Background: Several studies have shown that active compounds of Asclepias subulata (cardenolides) have antiproliferative effect on human cancer cells. Cardenolides isolated from A.
Wagner Vilegas +7 more
doaj +1 more source
Design, synthesis, in silico toxicity prediction, molecular docking, and evaluation of novel pyrazole derivatives as potential antiproliferative agents [PDF]
A new series of pyrazole derivatives were designed by docking into vascular endothelial growth factor receptor-2 (VEGFR-2) kinase active site. The designed compounds were synthesized and evaluated for in vitro antiproliferative activity against HT-29 ...
Chandra, Narendra Sharath JN +4 more
core +1 more source
Antiproliferative Activity of Vietnamese Medicinal Plants.
Methanol, methanol-water (1:1) and water extracts were prepared from seventy-seven Vietnamese medicinal plants and tested for their antiproliferative activities against human HT-1080 fibrosarcoma cells. Among them, fifteen extracts including seven methanol extracts of Caesalpinia sappan, Catharanthus roseus, Coscinium fenestratum, Eurycoma longifolia ...
Ueda, Jun-ya +7 more
openaire +4 more sources
Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids
Xanthohumol (XN) and four minor hops prenylflavonoids: α,β-dihydroxanthohumol (2HXN), isoxanthohumol (IXN), 8-prenylnaringenin (8PN), and 6-prenylnaringenin (6PN), were tested for antiproliferative activity towards human cancer and normal cell ...
Agnieszka Bartmańska +5 more
doaj +1 more source

