Results 81 to 90 of about 98,967 (297)
Investigating the Antiproliferative Activity of Synthetic Troponoids [PDF]
, 2016 Troponoid (more commonly, tropone/tropolone) refers to a family of naturally occurring compounds with a unique seven-membered aromatic ring. As with many secondary metabolites, many of the tropolones display a wide range of biological activity.
Falcone, Eric R
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Nanomaterials, 2018 Methotrexate is a folic acid antagonist and its incorporation into nanoformulations is a promising strategy to increase the drug antiproliferative effect on human breast cancer cells by overexpressing folate receptors.
Catiúscia P. de Oliveira +7 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang +7 more
wiley +1 more source
The Structure–Antiproliferative Activity Relationship of Pyridine Derivatives [PDF]
Pyridine, a compound with a heterocyclic structure, is a key player in medicinal chemistry and drug design. It is widely used as a framework for the design of biologically active molecules and is the second most common heterocycle in FDA-approved drugs ...
Mayra Lizett González-Félix +8 more
core +1 more source
Antiproliferative activity of terpene-phospholipids against human cancer cell lines. [PDF]
, 2017 Antiproliferative activity of terpene-phospholipids against human cancer cell lines.
Anna Gliszczyńska (2839163) +4 more
core +1 more source
Antiproliferative activity of arborescidine alkaloids and derivatives
European Journal of Medicinal Chemistry, 2009 Current issues in cancer research involve searching for novel anticancer compounds that can be used to regulate the cell cycle and lead to more effective treatments of tumors. In this study, it was hypothesized that possessing a cyclic alkaloid similar to harmine, arborescidines can disrupt the proliferative state of cancer cells and block the activity
Santos, Leonardo S. +3 more
openaire +6 more sources
Advanced Science, EarlyView.Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
New Catechol Derivatives of Safrole and Their Antiproliferative Activity towards Breast Cancer Cells
Molecules, 2011 Catechols were synthesized from safrole. Nine derivatives were prepared and assessed for antiproliferative effects using different human cell lines. The in vitro growth inhibition assay was based on the sulphorhodamine dye to quantify cell viability. The
Héctor Carrasco Altamirano +4 more
doaj +1 more source
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Atividade antioxidante e crioconcentração dos compostos bioativos do extrato aquoso de erva-mate (Ilex paraguariensis A. St. Hil.) [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2015.A atividade antioxidante do extrato aquoso de erva-mate está relacionada principalmente ...
Boaventura, Brunna Cristina Bremer
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