Results 11 to 20 of about 25,061 (213)
Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones [PDF]
Molecules, 2017 Cinnamaldehyde is a natural product with broad spectrum of antibacterial activity. In this work, it was used as a template for design and synthesis of a series of 17 cinnamylideneacetophenones. Phenolic compounds 3 and 4 exhibited MIC (minimum inhibitory
Carlos R. Polaquini +10 more
doaj +5 more sources
Antitubercular drug poisoning in a pregnant woman
Indian Journal of Anaesthesia, 2010 A 20-year-old female in her third month of pregnancy, presented with generalised tonic clonic seizures, metabolic acidosis and coma following suicidal ingestion of antitubercular medication.
Rahul Dutta +2 more
doaj +4 more sources
Recent Advances in Research on Antituberculars [PDF]
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Bhairab Nath Roy +2 more
openalex +5 more sources
Antitubercular pharmacodynamics of phenothiazines [PDF]
Journal of Antimicrobial Chemotherapy, 2012 Phenothiazines have been shown to exhibit in vitro and in vivo activity against Mycobacterium tuberculosis (Mtb) and multidrug-resistant Mtb. They are predicted to target the genetically validated respiratory chain component type II NADH:quinone oxidoreductase (Ndh).
Neil G. Berry +7 more
openaire +3 more sources
The Bewildering Antitubercular Action of Pyrazinamide [PDF]
Microbiology and Molecular Biology Reviews, 2020 Pyrazinamide (PZA) is a cornerstone antimicrobial drug used exclusively for the treatment of tuberculosis (TB). Due to its ability to shorten drug therapy by 3 months and reduce disease relapse rates, PZA is considered an irreplaceable component of standard first-line short-course therapy for drug-susceptible TB and second-line treatment regimens for ...
Elise A. Lamont +2 more
openaire +3 more sources
Exploration of Piperidinols as Potential Antitubercular Agents [PDF]
Molecules, 2014 Novel drugs to treat tuberculosis are required and the identification of potential targets is important. Piperidinols have been identified as potential antimycobacterial agents (MIC < 5 μg/mL), which also inhibit mycobacterial arylamine N-acetyltransferase (NAT), an enzyme essential for mycobacterial survival inside macrophages.
Areej Abuhammad +6 more
openaire +6 more sources
Molecules, 2021 Antimicrobial resistance was one of the top priorities for global public health before the start of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical landscape due to COVID-19, finding new organic structures with antimicrobial ...
Maria Marinescu
doaj +1 more source
Pharmacovigilance of Antitubercular Therapy in Tuberculosis [PDF]
Cureus, 2022 Background Adverse drug reactions (ADRs) to tuberculosis (TB) drugs are a significant concern for medical professionals and health authorities. Adverse events due to drug-resistant TB (DRTB) treatment are among the most important reasons for treatment interruption. Methods This study was an observational study conducted among patients diagnosed with TB
Ravichandran, Mirunalini +2 more
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Pleurisy in tuberculosis and HIV-infected patients
Журнал инфектологии, 2014 A clinical and epidemiological study for 14 years was conducted. Among TB patients, the percentage of persons with mixed infection (TB+HIV infection) increased during the observation period from 10 up to 64%. About one third of them had a pleura reaction
A. K. Ivanov +6 more
doaj +1 more source
Molecules, 2021 A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues.
Mashooq A. Bhat +4 more
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