Results 21 to 30 of about 39,598 (222)

Identification of 2-Amino Benzothiazoles with Bactericidal Activity against Mycobacterium tuberculosis

open access: yesMicrobiology Spectrum, 2023
We identified an amino-benzothiazole scaffold from a whole-cell screen against recombinant Mycobacterium tuberculosis under expressing the essential signal peptidase LepB. The seed molecule had 2-fold higher activity against the LepB hypomorph. Through a
Shilah Bonnett   +7 more
doaj   +1 more source

Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]

open access: yes, 2020
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca   +6 more
core   +1 more source

Synthesis and biological activity of 4-thiazolidinone derivatives of phenothiazine [PDF]

open access: yesJournal of the Serbian Chemical Society, 2012
A new series of N-[3-(10H-phenothiazinyl)-propyl]-2-(substituted phenyl)-4-oxo-5-( substituted benzylidene)-1,3-thiazolidine-carboxamide, 5(as) have been synthesized.
Sharma Ritu   +3 more
doaj   +1 more source

Intestinal Perforation as a Paradoxical Reaction to Antitubercular Therapy: A Case Report [PDF]

open access: yesAnnals of Coloproctology, 2021
Paradoxical reactions to tuberculosis (TB) treatment are characterized by an initial improvement of the clinical symptoms followed by clinical or radiological deterioration of existing tuberculous lesions, or by development of new lesions.
Sung Hoon Kang   +10 more
doaj   +1 more source

Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents

open access: yesPharmaceuticals, 2020
This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina   +3 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Multifunctional nanocarriers for lung drug delivery [PDF]

open access: yes, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core   +2 more sources

ChCl: Gly (DESs) Promote Environmentally Benign Synthesis of Xanthene Derivatives and Their Antitubercular Activity

open access: yesMolecules, 2021
A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues.
Mashooq A. Bhat   +4 more
doaj   +1 more source

THE SOCIAL AND CLINICAL CHARACTERISTIC OF PATIENTS WITH THE ISOLATED GENITAL TUBERCULOSIS ASSOCIATED WITH INFERTILITY, THE ACTIVE AND CLINICALLY CURED TUBERCULOSIS OF RESPIRATORY ORGANS IN COMBINATION WITH PREGNANCY

open access: yesБюллетень сибирской медицины, 2015
Due to the high incidence of tuberculosis of women of reproductive age research at 270 patients was conducted. The group of research included women with infertility and genital tuberculosis, pregnant women with active tuberculosis of lungs, pregnant ...
A. V. Mordyk   +3 more
doaj   +1 more source

Pleurisy in tuberculosis and HIV-infected patients

open access: yesЖурнал инфектологии, 2014
A clinical and epidemiological study for 14 years was conducted. Among TB patients, the percentage of persons with mixed infection (TB+HIV infection) increased during the observation period from 10 up to 64%. About one third of them had a pleura reaction
A. K. Ivanov   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy