Results 31 to 40 of about 35,652 (265)

Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria

Molecules, 2023
Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of antitubercular drugs.
Daniel J. Watson, Lubbe Wiesner, Tlhalefo Matimela, Denzil Beukes, Paul R. Meyers   +4 more
doaj   +1 more source

Steroid‐responsive aseptic meningitis with raised intracranial pressure syndrome associated with myelin oligodendrocyte glycoprotein autoantibodies

, 2022
Journal of Paediatrics and Child Health, Volume 58, Issue 12, Page 2322-2326, December 2022.
Wui‐Kwan Wong, Christopher Troedson, Ken Peacock, Fabienne Brilot‐Turville, Manoj P Menezes, Russell C Dale, Richard Webster   +6 more
wiley   +1 more source

Mechanochemical Synthesis and Physicochemical Characterization of Isoniazid and Pyrazinamide Co-crystals With Glutaric Acid

Frontiers in Chemistry, 2020
The present work reports two novel pharmaceutical co-crystals; 2:1 isoniazid-glutaric acid (INHGA) and 2:1 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first-line drugs used for the treatment of tuberculosis.
Jean Baptiste Ngilirabanga, Marique Aucamp, Paulo Pires Rosa, Halima Samsodien   +3 more
doaj   +1 more source

Pleurisy in tuberculosis and HIV-infected patients

Журнал инфектологии, 2014
A clinical and epidemiological study for 14 years was conducted. Among TB patients, the percentage of persons with mixed infection (TB+HIV infection) increased during the observation period from 10 up to 64%. About one third of them had a pleura reaction
A. K. Ivanov, G. V. Maksimov, S. L. Mukomolov, D. S. Esmеrdlayeva, M. Yu. Popov, T. L. Petrova, E. A. Malashenkov   +6 more
doaj   +1 more source

Study Of E-Smooth Support Vector Regression And Comparison With E- Support Vector Regression And Potential Support Vector Machines For Prediction For The Antitubercular Activity Of Oxazolines And Oxazoles Derivatives [PDF]

Published International Journal on Soft Computing, Artificial Intelligence and Applications (IJSCAI), Vol.2, No.2, April 2013, 2013
A new smoothing method for solving ? -support vector regression (?-SVR), tolerating a small error in fitting a given data sets nonlinearly is proposed in this study. Which is a smooth unconstrained optimization reformulation of the traditional linear programming associated with a ?-insensitive support vector regression. We term this redeveloped problem
arxiv   +1 more source

Targeted Isolation of Asperheptatides from a Coral-Derived Fungus Using LC-MS/MS-Based Molecular Networking and Antitubercular Activities of Modified Cinnamate Derivatives.

Journal of Natural Products, 2020
Under the guidance of MS/MS-based molecular networking, four new cycloheptapeptides, namely, asperheptatides A-D (1-4), were isolated together with three known analogues, asperversiamide A-C (5-7), from the coral-derived fungus Aspergillus versicolor ...
Rong Chao, Xue-Mei Hou, Wei-Feng Xu, Y. Hai, Mei-Yan Wei, Chang-Yun Wang, Yucheng Gu, C. Shao   +7 more
semanticscholar   +1 more source

Predictive Comparative QSAR Analysis Of As 5-Nitofuran-2-YL Derivatives Myco bacterium tuberculosis H37RV Inhibitors Bacterium Tuberculosis H37RV Inhibitors [PDF]

published Health Informatics- An International Journal (HIIJ) Vol.2, No.4, November 2013, 2013
Antitubercular activity of 5-nitrofuran-2-yl Derivatives series were subjected to Quantitative Structure Activity Relationship (QSAR) Analysis with an effort to derive and understand a correlation between the biological activity as response variable and different molecular descriptors as independent variables.
arxiv   +1 more source

Antitubercular therapy-induced psychosis [PDF]

Neurology, 2019
A 12-year-old girl with multidrug-resistant pulmonary tuberculosis presented with a 5-day history of headache and psychosis; at the time, she was taking a complex antitubercular therapy (ATT; kanamycin, levofloxacin, ethionamide, pyrazinamide, cycloserine, ethambutol) and pyridoxine. Examination revealed fluctuating sensorium and aggression.
Jitendra Kumar Sahu, Bhanudeep Singanamala, Lokesh Saini, Paramjeet Singh, Pankaj C Vaidya, Priyanka Madaan   +5 more
openaire   +3 more sources

Performance Analysis Of Regularized Linear Regression Models For Oxazolines And Oxazoles Derivitive Descriptor Dataset [PDF]

published International Journal of Computational Science and Information Technology (IJCSITY) Vol.1, No.4, November 2013, 2013
Regularized regression techniques for linear regression have been created the last few ten years to reduce the flaws of ordinary least squares regression with regard to prediction accuracy. In this paper, new methods for using regularized regression in model choice are introduced, and we distinguish the conditions in which regularized regression ...
arxiv   +1 more source

Performance Analysis Of Neural Network Models For Oxazolines And Oxazoles Derivatives Descriptor Dataset [PDF]

published International Journal of Information Sciences and Techniques (IJIST) Vol.3, No.6, November 2013, 2013
Neural networks have been used successfully to a broad range of areas such as business, data mining, drug discovery and biology. In medicine, neural networks have been applied widely in medical diagnosis, detection and evaluation of new drugs and treatment cost estimation.
arxiv   +1 more source