Results 41 to 50 of about 25,061 (213)
ChemMedChem, EarlyView.A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto +12 more
wiley +1 more source
Erythema multiforme due to antitubercular drugs
Lung India, 2011 Sameer Gulati +3 more
openalex +5 more sources
V. On the Antitubercular Action of Iodoform [PDF]
Annals of Surgery, 1887 n ...
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ChemMedChem, Accepted Article.Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore +5 more
wiley +1 more source
Synthesis and Biological Significance of Some 2-Azetidinone Derivatives [PDF]
Journal of Sciences, Islamic Republic of Iran, 2012 A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR,
P. Samadhiya
doaj
Food Biomacromolecules, EarlyView.The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar +5 more
wiley +1 more source
Antitubercular Triazines: Optimization and Intrabacterial Metabolism [PDF]
Cell Chemical Biology, 2020 The triazine antitubercular JSF-2019 was of interest due to its in vitro efficacy and the nitro group shared with the clinically relevant delamanid and pretomanid. JSF-2019 undergoes activation requiring F420H2 and one or more nitroreductases in addition to Ddn.
Xin Wang +25 more
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Quinoline: A promising antitubercular target
Biomedicine & Pharmacotherapy, 2014 Tuberculosis (TB) remains a global public health problem in recent years. TB originated mainly from various strains of Mycobacterium tuberculosis, is a highly infectious and chronic disease with high infection rate since ancient times. Since the last 50 years, the same long-duration, multidrug treatment plan is being followed for the treatment of ...
Rangappa S. Keri, Siddappa A. Patil
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Pathogens, 2018 Mycobacterium tuberculosis is the causative agent of tuberculosis, an ancient disease which, still today, represents a major threat for the world population. Despite the advances in medicine and the development of effective antitubercular drugs, the cure
Davide M. Ferraris +3 more
doaj +1 more source
Gut microbiota and tuberculosis
iMeta, EarlyView.This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu +39 more
wiley +1 more source