Results 61 to 70 of about 50,974 (272)
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda +7 more
wiley +1 more source
Cutaneous tuberculosis (scrofuloderma) in a five year-old boy: Case report [PDF]
Cutaneous tuberculosis (CTB) is a rare form of extrapulmonary TB in our region. The incidence of CTB seems to be increasing in some countries. CTB continues to be one of the most elusive and difficult diagnoses to make for dermatologists practicing in ...
Dehghan, M. +2 more
core
The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase [PDF]
EtaA is a newly identified FAD-containing monooxygenase that is responsible for activation of several thioamide prodrugs in Mycobacterium tuberculosis.
Fortin, R +3 more
core +2 more sources
ABSTRACT Objective To describe the diagnosis and treatment of a Mycobacterium avium (M. avium) infection in a cat following subdermal hyaluronic acid (HA) filler injection. Animal Studied A five‐year‐old spayed female domestic shorthair cat with chronic inferior lateral entropion and chronic feline atopic skin syndrome (FASS).
Alexandra E. Bergen +5 more
wiley +1 more source
Synthesis and Biological Significance of Some 2-Azetidinone Derivatives [PDF]
A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR,
P. Samadhiya
doaj
When you never thought it would be me
Tuberculosis, both pulmonary and extrapulmonary, is a procoagulant state, which can lead to deep-vein thrombosis and thromboembolism. Rifampicin, the antitubercular drug by itself, can cause a procoagulant state.
K R Raveendra +2 more
doaj +1 more source
Pulmonary tuberculosis (PTB) is associated with chronic inflammation and anemia. How anemia impacts systemic inflammation in PTB patients undergoing antitubercular therapy (ATT) is not fully understood.
Leonardo Gil-Santana +13 more
semanticscholar +1 more source
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source

