Results 61 to 70 of about 39,598 (222)

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

open access: yesArchiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová   +9 more
wiley   +1 more source

Drug metabolism by flavin-containing monooxygenases of human and mouse [PDF]

open access: yes, 2016
Introduction: Flavin-containing monooxygenases (FMOs) play an important role in drug metabolism. / Areas covered: We focus on the role of FMOs in the metabolism of drugs in human and mouse.
Phillips, IR, Shephard, EA
core   +1 more source

Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]

open access: yes, 2017
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang)   +5 more
core  

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam   +10 more
wiley   +1 more source

Synthetic Routes and Bioactivity Profiles of the Phenothiazine Privileged Scaffold

open access: yesOrganics
This review offers a focused overview of the strategies used to build and modify phenothiazine (PTZ) derivatives. It covers both classical synthetic approaches and advances reported since 2014, including transition metal-catalyzed transformations and ...
Aigul E. Malmakova, Alan M. Jones
doaj   +1 more source

Pneumothorax and Pneumomediastinum in a Sputum Positive Tuberculosis Patient: The Continuous Diaphragm Sign [PDF]

open access: yes, 2012
Secondary pneumothorax is a very common medical emergency. At times it is associated with pneumomediastinum, which could be fatal at times if not identified.
Bhatia, V   +5 more
core   +1 more source

Outcomes of Abdominal Tuberculosis Referred for Surgical Management in a Tertiary Care Center in Nepal

open access: yesJGH Open, Volume 10, Issue 1, January 2026.
ABSTRACT Background While abdominal tuberculosis (ATB) is a great masquerader, it can cause significant morbidity and mortality. We aim to evaluate the presentation and management outcomes of patients with abdominal TB referred to us for surgical management.
Kunal Bikram Deo   +4 more
wiley   +1 more source

Synthesis of (Z)-5-(substituted benzylidene)-2-((substituted phenyl) amino)thiazol-4(5H)-one analogues with antitubercular activity

open access: yesJournal of Taibah University for Science, 2019
We initiated a program to synthesize thiazolidinone derivatives as antitubercular agent by preparing hybrid molecules having the similar features of reported potent antitubercular agents.
Rohini N. Shelke   +6 more
doaj   +1 more source

Paradoxical Worsening of Tubercular Serpiginous-Like Choroiditis after Initiation of Antitubercular Therapy

open access: yesTürk Oftalmoloji Dergisi, 2016
In this study, a case with tubercular choroiditis showing severe macular edema and progression of choroidal lesions following initiation of antitubercular treatment is presented and the management of posterior uveitis associated with tuberculosis is ...
Ebru Esen   +3 more
doaj   +1 more source

Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions [PDF]

open access: yes, 2017
Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), one of the top 10 causes of death worldwide in 2015. The recent emergence of strains resistant to all current drugs urges the development of compounds with new mechanisms of action ...
Lavezzo, Enrico   +7 more
core   +1 more source

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