Results 71 to 80 of about 35,652 (265)
Journal of Taibah University for Science, 2019 We initiated a program to synthesize thiazolidinone derivatives as antitubercular agent by preparing hybrid molecules having the similar features of reported potent antitubercular agents.
Rohini N. Shelke +6 more
doaj +1 more source
Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy
Advanced Therapeutics, Volume 8, Issue 4, April 2025.Tuberculosis (TB) remains a global health challenge, with drug‐resistant strains exacerbating the issue. Metallic nanoparticles (MNPs) show promise in TB diagnosis as sensor probes and in combination therapy with antimycobacterial drugs, requiring further pre‐clinical and clinical research for clinical translation.
Christianah Aarinola Akinnawo +1 more
wiley +1 more source
Organic Letters, 2019 Atrovimycin (1), a cyclodepsipeptide containing a unique vicinal-hydroxylated cinnamic acyl chain, was isolated and elucidated from Streptomyces atrovirens LQ13.
Qing Liu +8 more
semanticscholar +1 more source
ChemBioChem, Volume 26, Issue 7, April 1, 2025.The biarylitides are fascinating RiPP natural products with small core peptides and diverse peptide crosslinks performed by cytochrome P450 enzymes. Here, we address the discovery and diversity of the biarylitides, methods to analyse these constrained cyclic peptides, the structures of the biarylitide P450 enzymes and address alternate catalytic ...
Leo Padva +6 more
wiley +1 more source
Direct Inhibition of MmpL3 by Novel Antitubercular Compounds
ACS Infectious Diseases, 2019 MmpL3, an essential transporter involved in the export of mycolic acids, is the proposed target of a number of antimycobacterial inhibitors under development.
Wei Li +9 more
semanticscholar +1 more source
Antitubercular activity of trifluoperazine, a calmodulin antagonist [PDF]
FEMS Microbiology Letters, 1992 Trifluoperazine, a calmodulin antagonist, completely inhibited the growth of mycobacteria. The minimum inhibitory concentrations in shake cultures in a synthetic medium containing 0.2% Tween 80 were 5 and 8 micrograms/ml, respectively, for the human pathogenic strain Mycobacterium tuberculosis H37Rv and M. tuberculosis resistant to isoniazid.
P. Ratnakar, P. Suryanarayana Murthy
openaire +3 more sources
Health Science Reports, Volume 8, Issue 4, April 2025.ABSTRACT Background Medication use (MU) during pregnancy can increase the risk of maternal and fetal health consequences. Women's knowledge, attitude, and practice (KAP) regarding safe MU can influence pregnancy outcomes. The study aimed to assess and explore women's KAP regarding safe MU during pregnancy and identify possible determinants.
Musiime Brian +10 more
wiley +1 more source
PYRAZINAMIDE INDUCED ACUTE GOUTY ARTHRITIS
Journal of Nepal Medical Association, 2003 A typical case of pyrazinamide induced acute gouty arthritis in a tuberculous patient with antitubercular therapy including pyrazinamide was reported.
U N Pathak, B O Shrestha, R R Shrestha
doaj +1 more source
Predictive Comparative QSAR analysis of Sulfathiazole Analogues as Mycobacterium Tuberculosis H37RV Inhabitors [PDF]
published 2012, 2014 Antitubercular activity of Sulfathiazole Derivitives series were subjected to Quantitative Structure Activity Relationship (QSAR) Analysis with an attempt to derive and understand a correlation between the Biologically Activity as dependent variable and various descriptors as independent variables. QSAR models generated using 28 compounds.
arxiv
Health Science Reports, Volume 8, Issue 4, April 2025.ABSTRACT Background and Aims Drug‐induced renal vasculitis arises from various medications that cause immunological dysregulation or direct vascular damage, leading to inflammation and thrombosis. Clinical manifestations vary widely, from mild constitutional symptoms to severe organ dysfunction. This review aims to thoroughly explore drug‐induced renal
Hashim Mohamed Siraj +7 more
wiley +1 more source