Results 71 to 80 of about 25,061 (213)

Synthesis and Biological Assessment of Cyanopyridine‐Based 1,3,4‐Oxadiazole Derivatives: Anticancer Potential, Antioxidant Activity, Molecular Docking, and DFT Calculations

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
A series of novel cyanopyridine‐based 1,3,4‐oxadiazole derivatives were synthesized, and their anticancer activities against the MCF‐7 and CaCo‐2 cancer cell lines, as well as their antioxidant capacities, were evaluated under In Vitro conditions. Furthermore, computational studies utilizing Density Functional Theory (DFT) and molecular modeling were ...
Zineddine Zebbiche   +6 more
wiley   +1 more source

The Halo Vest Immobilization for Craniocervical Junction Tuberculosis: A Comparison of Treatment Options

open access: yesOrthopaedic Surgery, Volume 17, Issue 6, Page 1732-1741, June 2025.
This study aimed to evaluate the clinical outcomes and safety of Halo vest (HV) immobilization in treating craniovertebral junction tuberculosis, compared with occipitocervical fusion. The results showed that patients receiving HV treatment had greater improvement in neck function compared with those undergoing occipitocervical fusion.
Yunfeng Wu   +5 more
wiley   +1 more source

Ligand-based discovery of novel N-arylpyrrole derivatives as broad-spectrum antimicrobial agents with antibiofilm and anti-virulence activity

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
The escalating threat of antimicrobial resistance calls for novel therapeutic agents. This study employed a ligand-based design approach to develop three series of N-arylpyrrole derivatives (Va–e, VIa–e, and VIIa–e), refined through molecular modeling ...
Basma M. Qandeel   +5 more
doaj   +1 more source

Liver transplantation for acute liver failure due to antitubercular drugs – a single-center experience

open access: yesClinics, 2018
OBJECTIVES: Patients receiving treatment for tuberculosis are at risk of developing acute liver failure due to the hepatotoxicity of antitubercular drugs.
Rodrigo Bronze de Martino   +4 more
doaj   +1 more source

Hepatitis C virus infection: a challenge in the complex management of two cases of multidrug-resistant tuberculosis

open access: yesBMC Infectious Diseases, 2019
Background Multidrug-resistant tuberculosis (MDR-TB) requires lengthy use of second-line drugs, burdened by many side effects. Hepatitis C virus (HCV) chronic infection increases risk of drug-induced liver injury (DILI) in these patients.
Maria Musso   +9 more
doaj   +1 more source

Histomorphological features of combined forms of tuberculosis and lung cancer [PDF]

open access: yesMedičnì Perspektivi, 2017
The were studied pathological features of combined forms of tuberculosis and non-small cell lung cancer in 72 patients who underwent radical surgical resection interventions from transsternal access with mediastinal lymph node dissection, with ...
Savenkov Y.F.   +4 more
doaj  

Development of Pseudomembranous Colitis Four Months after Initiation of Rifampicin

open access: yesCase Reports in Gastroenterology, 2011
Pseudomembranous colitis (PMC) may develop with long-term antibiotic administration, but is rarely reported to be caused by antitubercular agents. We present a case of PMC that occurred 120 days after starting rifampicin.
Jeong Moon Choi   +4 more
doaj   +1 more source

Successful desensitization for antitubercular drugs

open access: yesAllergy, Asthma & Respiratory Disease, 2013
Ae-Ra Lee, Soo Jung Kim, Junghyun Kim, Ju-Hee Park, Jung-Kyu Lee, Ju-Young Kim, Suh-Young Lee, Hye-Ryun Kang Department of Internal Medicine, Seoul National University College of Medicine, Seoul; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul National University College of Medicine, Seoul ...
Ju Young Kim   +9 more
openaire   +2 more sources

Studies on new substituted pyridazinones: synthesis and biological evaluation

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2018
We report herein the synthesis and pharmacological evaluation of a new series of 6-aryl-2-(imidazol-1-yl/1,2,4-triazol-1-yl)-2-methyl-4,5-dihydro-(2H)-pyridazin-3-one (3a-j) as potential anticonvulsant and antitubercular agents.
Mohammad Asif   +3 more
doaj   +1 more source

Quality of the life of the TB patients

open access: yesКубанский научный медицинский вестник, 2015
In the article the results of studying the quality of the life of patients with tuberculosis are represented. By the authors were interviewed 500 patients GBUz SK «Boundary antitubercular dispensary» (g. Stavropol').
V. B. Zafirova   +3 more
doaj  

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