Results 141 to 150 of about 3,270,661 (190)

Salicylhydroxamic Acid as an Antitubercular Agent

Nature, 1950
SOME derivatives of salicylic acid possess antitubercular properties, the most important of such substances being the well-known p-aminosalicylic acid used by Lehmann1. Nevertheless, numerous investigations seem to indicate that most of the antitubercular compounds contain amino-groups.
openaire   +2 more sources

Discovery of 1,2,3-triazole incorporated indole-piperazines as potent antitubercular agents: Design, synthesis, in vitro biological evaluation, molecular docking and ADME studies.

Bioorganic & Medicinal Chemistry, 2023
Rajkumar Reddyrajula, Umadevi Etikyala, V. Manga, Udaya Kumar Dalimba   +3 more
semanticscholar   +1 more source

[Antitubercular agents].

Therapeutische Umschau. Revue therapeutique, 2000
The personally experienced development of chemotherapy for tuberculosis during the last half century represents some highlights of new knowledges and practical successes: the discovery of antituberculosis drugs; the comprehension of their actions and side effects; the exploration of mechanisms of resistance against antituberculosis agents; the ...
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Antitubercular Agents. Part 1. Synthesis of Phthalimido‐ and Naphthalimido‐Linked Phenazines as New Prototype Antitubercular Agents.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ahmed, Kamal, A, Hari Babu, A, Venkata Ramana, Rakesh, Sinha, J S, Yadav, Sudarshan K, Arora   +5 more
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Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-D-ribofuranose 2'-Oxidase.

Journal of Medicinal Chemistry, 2019
We report herein the discovery of 3,5-dinitrophenyl 1,2,4-triazoles with excellent and selective antimycobacterial activities against Mycobacterium tuberculosis strains, including clinically isolated multidrug-resistant strains.
Galina Karabanovich, J. Dušek, Karin Savková, O. Pavliš, I. Pavkova, J. Korábečný, T. Kučera, Hana Kočová Vlčková, Stanislav Huszár, Zuzana Konyariková, K. Konečná, O. Jand’ourek, J. Stolaříková, Jana Korduláková, K. Vávrová, P. Pávek, V. Klimešová, A. Hrabálek, K. Mikušová, Jaroslav Roh   +19 more
semanticscholar   +1 more source

Design, synthesis, and biological evaluation of 1,2,4-triazole derivatives as potent antitubercular agents

Chinese Chemical Letters, 2023
Yu Wen, S. Lun, Yuxue Jiao, Wei Zhang, T. Hu, Ting Liu, Fan Yang, Jie Tang, Bing Zhang, W. Bishai, Lifang Yu   +10 more
semanticscholar   +1 more source

Design, synthesis, and computational studies of benzimidazole derivatives as new antitubercular agents

Journal of Biomolecular Structure and Dynamics, 2022
Gozde Yalcin-Ozkat, Ronak Haj Ersan, M. Ulger, S. Ulger, Serdar Burmaoglu, Ilkay Yildiz, Oztekin Algul   +6 more
semanticscholar   +1 more source

Antitubercular Agents

Antitubercular agents are medications used to treat tuberculosis (TB), a serious infectious disease caused by Mycobacterium tuberculosis. These agents are categorized into first-line and second-line drugs based on their efficacy, toxicity, and role in TB treatment regimens. First-line antitubercular drugs, such as isoniazid, rifampin, pyrazinamide, and
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Synthesis of some novel piperidine fused 5-thioxo-1H-1,2,4-triazoles as potential antimicrobial and antitubercular agents

Proceedings of the Indian Academy of sciences. Chemical sciences, 2021
R. Rishikesan, R. P. Karuvalam, Nibin Joy Muthipeedika, Ayyiliath M Sajith, K. Eeda, Rajeesh Pakkath, K. Haridas, Vaishnav Bhaskar, K. H. Narasimhamurthy, A. Muralidharan   +9 more
semanticscholar   +1 more source

[Oral desensitization to antitubercular agents].

Revue de pneumologie clinique, 1997
We report a case of hypersensitivity reaction to majors antituberculosis drugs. We have successfully performed oral desensitization to "Rifater *". We present our protocol that we compare to those proposed in the literature.
I, Drira, R, Souissi, R, Dakhlaoui, M S, Jeguirim, M L, Chebbi   +4 more
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