Results 181 to 190 of about 16,306 (216)

Dihydroartemisinin and its Analogs: A New Class of Antitubercular Agents

Current Topics in Medicinal Chemistry, 2019
Background: Tuberculosis is one of the leading causes of mortality worldwide. Resistance against the frontline anti-tubercular drugs has worsened the already alarming situation, which requires intensive drug discovery to develop new, more effective, affordable and accessible anti-tubercular agents possessing novel modes of action.
Komal Kalani, Sudeep Tondon, Vinita Chaturvedi, Santosh K. Srivastava, Priyanka Trivedi   +4 more
openaire   +3 more sources

Novel dihydropyrimidines as a potential new class of antitubercular agents

Bioorganic & Medicinal Chemistry Letters, 2010
A small library of 30 dihydropyrimidines was synthesized and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H(37)Rv. Two compounds, ethyl 4-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5 carboxylate 4a and ethyl 4-[3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl]-6-methyl ...
Vipul B. Kataria, Amit R. Trivedi, Viresh H. Shah, Dipti K. Dodiya, Bipin H. Dholariya, Vimal R. Bhuva   +5 more
openaire   +3 more sources

Current Affairs, Future Perspectives of Tuberculosis and Antitubercular Agents

Indian Journal of Tuberculosis, 2018
Tuberculosis (TB) is the major threat for humans from past several decades. Even after advent of several antitubercular drugs, researchers are still struggling for the mycobacterial infections in humans are TB and leprosy. Chronic infections caused by Mycobacterium tuberculosis and Mycobacterium leprae. A particular problem with both of these organisms
Chandrakant G. Bonde, Jineetkumar Gawad
openaire   +3 more sources

Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review

Infectious Disorders - Drug Targets, 2015
Hydrazones are a versatile linker of connecting various classes of organic compounds with a unique structural feature of hydrogen bonding donor and the hydrogen bonding acceptor region. An extensive number of research has been carried out on hydrazone derivatives as a potent class of antitubercular agents.
Mohamed Jawed Ahsan, Githa Elizabeth Mathew, Kallivalappil Fathima Safna, Puthucode Natarajan Shiva Subramanyan, Srinubabu Maddela, Jerad Suresh, Dhasthakeer Usman, Bijo Mathew   +7 more
openaire   +3 more sources

1,5-Diarylpyrroles as potent antitubercular and anti-inflammatory agents

Chemistry of Heterocyclic Compounds, 2017
This minireview surveys the work of our research group directed toward finding novel antimycobacterial and anti-inflammatory drugs. Many active compounds were found with a common 1,5-diarylpyrrole skeleton. Some of the synthesized compounds, designed on the basis of structure–activity relationship studies, showed very interesting activities and proved ...
VENDITTI, GIULIA, POCE, Giovanna, CONSALVI, SARA, BIAVA, Mariangela   +3 more
openaire   +2 more sources

Antifungal, Antitubercular, and Antiviral Agents

Seminars in Dialysis, 1988
William F. Keane, Gary R. Matzke, Michael H. Schwenk   +2 more
openaire   +2 more sources

Molecular imaging in oncology: Current impact and future directions

Ca-A Cancer Journal for Clinicians, 2022
Steven P Rowe, Martin G Pomper
exaly  

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Recent progress in the treatment of cancer in children

Ca-A Cancer Journal for Clinicians, 2021
Theodore W Laetsch
exaly