Results 71 to 80 of about 7,631 (195)

Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3 [PDF]

, 2017
In previous studies using mice with macrophage-specific loss of TRPC3 we found a significant, selective effect of TRPC3 on the biology of M1, or inflammatory macrophages.
Atolagbe, Oluwatomisin T., Birnbaumer, Lutz, Joe, Bina, Kumarasamy, Sivarajan, Solanki, Sumeet, Vazquez, Guillermo   +5 more
core   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, Volume 16, Issue 2, Page 397-411, February 2026.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Directed DNA deamination by AID/APOBEC3 in immunity [PDF]

Current Biology, 2006
The important contributions of many investigators could not be specifically cited due to space considerations, but many of these can be found within the bibliography. We thank Tim Behrens, Bill Brown, Eric Hendrickson, Stefan Jonsson and Michael Neuberger for thoughtful comments on this manuscript. R.S.H. is supported in part by a Searle Scholarship, a
MacDuff, Donna A., Harris, Reuben S.
openaire   +2 more sources

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

Cancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B [PDF]

, 2014
Several recent studies have converged upon the innate immune DNA cytosine deaminase APOBEC3B (A3B) as a significant source of genomic uracil lesions and mutagenesis in multiple human cancers, including those of the breast, head/neck, cervix, bladder ...
Harris, Reuben S., Howley, Peter M., Lambert, Paul F., Lee, Denis, Leonard, Brandon, Lorenz, Laurel D., Soares, Marcelo A., Starrett, Gabriel J., Temiz, Nuri A., Vieira, Valdimara C., White, Elizabeth A.   +10 more
core   +1 more source

HIV Types, Groups, Subtypes and Recombinant Forms: Errors in Replication, Selection Pressure and Quasispecies [PDF]

, 2012
HIV-1 is a chimpanzee virus which was transmitted to humans by several zoonotic events resulting in infection with HIV-1 groups M P, and in parallel transmission events from sooty mangabey monkey viruses leading to infections with HIV-2 groups A H.
Alvarez M, Batmanian J, Bocharov G, Brennan CA, Burgard M, Buzon MJ, Dahl V, Dai L, Domingo E, Duarte EA, Etienne L, Fang G, Fultz PN, Gunthard HF, Henriet S, Iordanskiy S, Josef Eberle, Julg B, Kijak GH, Korber B, Law M, Lemey P, Lorenzo-Redondo R, Lutz G. Gürtler, Motomura K, Neel C, Onafuwa-Nuga A, Pathak VK, Pathak VK, Rachinger A, Sauter D, Shimizu N, Simon-Loriere E, Smith DM, Sterjovski J, Swenson LC, Tienen C, Troyer JL, Van der Kuyl AC, Van der Vlist M, Zhu T   +40 more
core   +1 more source

Navigating the Public Health Challenges of 2024: A Multisectoral Approach to Global Health Resilience, Equity, and Innovation

Advances in Public Health, Volume 2026, Issue 1, 2026.
The global public health landscape in 2024 is defined by overlapping crises that strain health systems, deepen inequities, and demand urgent multisectoral responses. This comprehensive review examines the critical intersection of these challenges.
Olalekan John Okesanya, Jerico Bautista Ogaya, Mohamed Mustaf Ahmed, Md Faiazul Haque Lamem, Tolga Kab, Yasir Ahmed Mohammed Elhadi, Shuaibu Saidu Musa, Gilbert Eshun, Tolutope Adebimpe Oso, Don Eliseo Lucero-Prisno III, Hannah Wesley   +10 more
wiley   +1 more source

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3

Virology, 2014
Humans encode seven APOBEC3 (A3A-A3H) cytidine deaminase proteins that differ in their expression profiles, preferred nucleotide recognition sequence and capacity for restriction of RNA and DNA viruses. We identified APOBEC3 hotspots in numerous herpesvirus genomes.
Minkah, Nana, Chavez, Kevin, Shah, Parth, MacCarthy, Thomas, Chen, Hui, Landau, Nathaniel, Krug, Laurie T.   +6 more
openaire   +2 more sources

High-level of viral genomic diversity in cervical cancers: a Brazilian study on human papillomavirus type 16 [PDF]

, 2015
Invasive cervical cancer (ICC) is the third most frequent cancer among women worldwide and is associated with persistent infection by carcinogenic human papillomaviruses (HPVs).
Adhemar Longatto-Filho, Akagi, Antonsson, Aromseree, Beckman, Bernard, Bouvard, Bragg, Bravo, Bravo, Bruni, Burk, Byrne, Canadas, Chen, Chen, Chen, Cristina Mendes de Oliveira, Cubie, Dall, de Oliveira, de Sanjose, de Sanjose, de Villiers, De Vuyst, Dillner, DiLorenzo, Doorbar, Doorbar, Edgar, Flores, Freitas, Gheit, Ignacio G. Bravo, Jesus Paula Carvalho, José Eduardo Levi, José Humberto Tavares Guerreiro Fregnani, Kukimoto, Levi, Li, Li, Liu, Loeb, Maria Luiza Nogueira Dias Genta, Maricy Tacla, Munk, Murray, Nathália Caroline Santiago e Souza, Orav, Quint, Rebollo, Smith, Stamatakis, Sun, Thorvaldsdottir, Valmary-Degano, Vartanian, Walboomers, Wang, Wang, Watts, Wentzensen, Xu, Yuan   +63 more
core   +1 more source

Extranodal NK/T‐Cell Lymphoma, Nasal Type of Head and Neck in a Pediatric Population: A Systematic Review

European Journal of Cancer Care, Volume 2026, Issue 1, 2026.
Objective This review aims to identify and evaluate the management options for the extranodal NK/T‐cell lymphoma, nasal type of head and neck in the pediatric population. Methods The study was conducted based on a comprehensive literature review from 2009 to 2025. The following keywords were used: extranodal NK/T cell lymphoma and children and head and
Agata Gierlotka, Ireneusz Bielecki, Joanna Sordyl, Agnieszka Mizia-Malarz, Tarcilia Silva   +4 more
wiley   +1 more source