Results 121 to 130 of about 2,316 (158)

Surface-Modified Nanozymes for Enhanced and Selective Catalysis. [PDF]

ACS Appl Mater Interfaces
Chen X, Willner I.
europepmc   +1 more source

Nucleic Acid-Modified Nanoparticles for Cancer Therapeutic Applications. [PDF]

Small
Qin Y, Chen X, Willner I.
europepmc   +1 more source

A "metabolic dual-clamp" strategy for glucose metabolism blockade and cascade-amplified tumor immunotherapy. [PDF]

Mater Today Bio
Chang P, Yang X, Chen D, Tian K, Liu S, Li K, Chen D, Liu C, Wang W, Pan Q, Zeng Y, Zhan Y, Zhan W.   +12 more
europepmc   +1 more source

Framework Nucleic Acids as a Nanocontainer for Delivering Heterogeneous Molecular Drugs. [PDF]

Pharmaceutics
Yang M, Lou X, Song J, Wang J, Peng H, Wang L.   +5 more
europepmc   +1 more source

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Therapeutic applications of AS1411 aptamer, an update review

International Journal of Biological Macromolecules, 2020
Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus. However, in several cancers, nucleolin is highly expressed both intracellularly and on the cell surface. So, it is considered as a potential target for the diagnosis and cancer therapy.
Rezvan Yazdian–Robati, Fatemeh Oroojalian, Mehryar Zargari   +2 more
exaly   +3 more sources

The effect of AS1411 aptamer on anti-tumor effects of dendrimers containing SN38

Journal of Drug Delivery Science and Technology, 2022
Seyedeh Alia Moosavian, Bizhan Malaekeh-Nikouei   +1 more
exaly   +2 more sources

Corneal neovascularization is inhibited with nucleolin-binding aptamer, AS1411

Experimental Eye Research, 2020
Corneal neovascularization (CNV) is a common sight-threatening pathology that can be induced by a variety of inflammatory and angiogenic stimuli. Current CNV treatments include anti-inflammatory drugs and antibody-based inhibitors of vascular endothelial growth factor (VEGF).
Oscar, Vivanco-Rojas, Mariana Y, García-Bermúdez, Emilio, Iturriaga-Goyon, Wolfgang, Rebollo, Beatriz, Buentello-Volante, Fátima S, Magaña-Guerrero, Paula, Bates, Armando, Pérez-Torres, Yonathan, Garfias   +8 more
openaire   +2 more sources

Aptamer AS1411 utilized for super-resolution imaging of nucleolin

Talanta, 2020
Nucleolin (NCL) is a multifunctional protein that mainly localizes in the nucleolus and also distributes in the nucleoplasm, cytoplasm and cell membrane. Most studies focus on its biofunctions in cell activities and diseases, however, its detailed distribution and organization pattern in situ remains obscure.
Yingying, Jing, Mingjun, Cai, Lulu, Zhou, Junguang, Jiang, Jing, Gao, Hongda, Wang   +5 more
openaire   +2 more sources

Aptamer imaging with Cu-64 labeled AS1411: Preliminary assessment in lung cancer

Nuclear Medicine and Biology, 2014
AS1411 is a 26-base guanine-rich oligonucleotide aptamer shown binding to surface nucleolin, a protein over-expressed in multiple cancer cells, thus AS1411 labeled with a PET isotope can be explored as a potential diagnostic imaging agent. Our objective was to perform preliminary biological characterization of (64)Cu-labeled AS1411 in vitro and in vivo.
Junling Li, Tariq Malik, John O Trent
exaly   +3 more sources