Results 101 to 110 of about 24,501 (255)

Results of pRNFL and segmented macular layer measurements in AQP4-Ab-positive ON, AQP4-Ab-negative ON and HC cohorts.

, 2016
Results of pRNFL and segmented macular layer measurements in AQP4-Ab-positive ON, AQP4-Ab-negative ON and HC cohorts.
Huanfen Zhou (2852270), Shihui Wei (580991), Hongyang Li (296731), Quangang Xu (114116), Chunxia Peng (2634328), Mo Yang (507360), Wei Wang (17594), Shuo Zhao (1545043), Shanshan Cao (2852267)   +8 more
core   +1 more source

Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2018
Background Pain is a frequent symptom in aquaporin-4-immunoglobulin-G-positive neuromyelitis optica spectrum disorders (AQP4-IgG-pos. NMOSD). Data on pain in myelin-oligodendrocyte-glycoprotein-immunoglobulin-G autoimmunity with a clinical NMOSD ...
Susanna Asseyer, Felix Schmidt, Claudia Chien, Michael Scheel, Klemens Ruprecht, Judith Bellmann-Strobl, Alexander U Brandt, Friedemann Paul   +7 more
doaj   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Correlation between AQP4-M1 CDS cloning strategy, LS frequency, the AQP4-M1/M23 ratio and NMO-IgG binding.

, 2013
(A): Immunoblot experiment performed using commercial AQP4 antibodies on cells transfected with different AQP4 expressing constructs. From the left: lane 1, AQP4-M23 exclusively producing AQP4-M23, lane 2, AQP4-M1M23I (with the methionine in position 23 ...
Angelo Sparaneo (387329), Maddalena Ruggieri (485748), Maria Grazia Mola (387330), Maria Trojano (301639), Carla Tortorella (301673), Antonio Frigeri (352675), Francesco Pisani (387328), Grazia Paola Nicchia (352672), Maria Svelto (330761)   +8 more
core   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

Astrocyte‐Associated ABCA1/APOE Responses Accompany Hippocampal Lipid Remodeling and Ectopic Neuronal Accumulation During Epileptogenesis

Advanced Science, EarlyView.
During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen, Xiao‐Rui Shi, Jia‐Yi Chen, Ying‐Ting Wang, Le Du, Yang Ni, Jun‐Min Chen, An‐Chen Guo, Qian Wu, Jian‐Ping Wu, Qun Wang   +10 more
wiley   +1 more source

Western blot analysis of AQP4 protein expression in each normal AQP4^+/+ group.

, 2013
(A, B) Western blot analysis showed rhVEGF165 injected intracerebroventricularly up-regulated AQP4 protein expression at striatum in normal AQP4+/+ mice at 1 d, 3 d, and 7 d (n = 6 ...
Yuping Tang (249674), Qiang Dong (380835), Heling Chu (425189)   +2 more
core   +1 more source

RETRACTED: AQP4-dependent water transport plays a functional role in exercise-induced skeletal muscle adaptations.

PLoS ONE, 2013
In this study we assess the functional role of Aquaporin-4 (AQP4) in the skeletal muscle by analyzing whether physical activity modulates AQP4 expression and whether the absence of AQP4 has an effect on osmotic behavior, muscle contractile properties ...
Davide Basco, Bert Blaauw, Francesco Pisani, Angelo Sparaneo, Grazia Paola Nicchia, Maria Grazia Mola, Carlo Reggiani, Maria Svelto, Antonio Frigeri   +8 more
doaj   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source