Results 31 to 40 of about 8,136 (194)

Zoonotic aspects of arenavirus infections [PDF]

Veterinary Microbiology, 2010
To date, the International Committee for Taxonomy of Viruses recognizes that the family Arenaviridae contains a unique genus Arenavirus that includes 22 viral species. There are nine additional arenaviruses that either have been discovered recently, or which taxonomic status remains pending.
Charrel, R.N., de Lamballerie, X.
openaire   +3 more sources

Envelope exchange for the generation of live-attenuated arenavirus vaccines. [PDF]

PLoS Pathogens, 2006
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical ...
Andreas Bergthaler, Nicolas U Gerber, Doron Merkler, Edit Horvath, Juan Carlos de la Torre, Daniel D Pinschewer   +5 more
doaj   +2 more sources

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]

, 2010
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi, Jason Botten, Matt Maybeno, John Sidney, Jean Glenn, Huynh-Hoa Bui, Carla Oseroff, Shane Crotty, Bjoern Peters, Howard Grey, Daniel M Altmann, Michael J Buchmeier, Alessandro Sette   +12 more
core   +2 more sources

CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor

Viruses, 2021
Lassa virus (LASV)—a member of the family Arenaviridae—causes Lassa fever in humans and is endemic in West Africa. Currently, no approved drugs are available.
Toru Takenaga, Zihan Zhang, Yukiko Muramoto, Sarah Katharina Fehling, Ai Hirabayashi, Yuki Takamatsu, Junichi Kajikawa, Sho Miyamoto, Masahiro Nakano, Shuzo Urata, Allison Groseth, Thomas Strecker, Takeshi Noda   +12 more
doaj   +1 more source

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever. [PDF]

, 2014
International audienceThe pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated ...
A Mantovani, A Wack, B Moser, C Pythoud, C-L Lin, D Cook, D Pannetier, D Pannetier, D Whiting, DD Pinschewer, DD Taub, DD Taub, DD Taub, Delphine Pannetier, DH Walker, DH Walker, F Castellino, H Sung Jung, H Wulff, IS Lukashevich, J ter Meulen, J ter Meulen, JB McCormick, JB McCormick, JE Christensen, JF Foley, JH Dufour, JR Groom, KM Hastie, KM Johnson, L Hensley, L Martinez-Sobrido, L Martinez-Sobrido, LL Xu, M Habjan, M Inngjerdingen, M Liu, M Loetscher, M Macal, M Perez, M Russier, M-F Hsieh, Marion Russier, MD Bowen, MM Djavani, MP Kiley, N Sogoba, O Lenz, R Lande, S Baize, S Baize, S Baize, S Deshmane, S Günther, S Mahanty, S Mahanty, S Malhotra, SL Ruo, Stéphanie Reynard, Sylvain Baize, T Strecker, Thomas Geisbert, TI Cornu, TJ Schall, W Cao, WWSI Rodrigo, X Carnec, X Qi, Xavier Carnec   +68 more
core   +8 more sources

Serological Assays Based on Recombinant Viral Proteins for the Diagnosis of Arenavirus Hemorrhagic Fevers

Viruses, 2012
The family Arenaviridae, genus Arenavirus, consists of two phylogenetically independent groups: Old World (OW) and New World (NW) complexes. The Lassa and Lujo viruses in the OW complex and the Guanarito, Junin, Machupo, Sabia, and Chapare viruses in the
Masayuki Saijo, Shigeru Morikawa, Tomoki Yoshikawa, Hideki Tani, Shuetsu Fukushi   +4 more
doaj   +1 more source

Seroprevalence of arenavirus and hantavirus in indigenous populations from the Caribbean, Colombia

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel ...
Amada Bolaños, Carolina Montoya-Ruiz, Juan Camilo Perez-Peréz, Juan David Rodas, Salim Mattar   +4 more
doaj   +1 more source

A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease. [PDF]

, 2016
UNLABELLED: Arenaviruses are emerging viruses including several causative agents of severe hemorrhagic fevers in humans. The advent of next-generation sequencing technology has greatly accelerated the discovery of novel arenavirus species.
Bergeron, E., Burri, D.J., da Palma, J.R., Khatib, A.M., Kunz, S., Oppliger, J., Pasquato, A., Spiropoulou, C.F.   +7 more
core   +1 more source

New arenavirus isolated in Brazil [PDF]

The Lancet, 1994
A new arenavirus, called Sabiá, was isolated in Brazil from a fatal case of haemorrhagic fever initially thought to be yellow fever. Antigenic and molecular characterisation indicated that Sabiá virus is a new member of the Tacaribe complex. A laboratory technician working with the agent was also infected and developed a prolonged, non-fatal influenza ...
Coimbra, T.L.M., Nassar, E.S., Burattini, M.N., Madia de Souza, L.T., Ferreira, I.B., Rocco, I.M., Travassos da Rosa, A.P.A., Vasconcelos, P.F.C., Pinheiro, F.P., Le Duc, J.W., Rico-Hesse, R., /Gonzalez, Jean-Paul, Jahrling, P.B., Tesh, R.B.   +13 more
openaire   +3 more sources

Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity

Frontiers in Microbiology, 2022
In the absence of effective vaccines and treatments, annual outbreaks of severe human haemorrhagic fever caused by arenaviruses, such as Lassa virus, continue to pose a significant human health threat.
Robert J. Stott-Marshall, Toshana L. Foster   +1 more
doaj   +1 more source