Results 61 to 70 of about 8,136 (194)
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis.
PLoS Pathogens, 2020 Pathogenicity often differs dramatically among even closely related arenavirus species. For instance, Junín virus (JUNV), the causative agent of Argentine hemorrhagic fever (AHF), is closely related to Tacaribe virus (TCRV), which is normally avirulent ...
Julia Holzerland +5 more
doaj +1 more source
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression [PDF]
, 2017 Immune-mediated effector molecules can limit cancer growth, but lack of sustained immune activation in the tumour microenvironment restricts antitumour immunity.
Gassa, Asmae +8 more
core +1 more source
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
Advanced Science, Volume 13, Issue 12, 27 February 2026.During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source
Emerging Infectious Diseases, 2001 The purpose of this study was to extend our knowledge of the geographic distribution and genetic diversity of the arenavirus(es) associated with Neotoma species (woodrats) in the southwestern United States.
Charles F. Fulhorst +7 more
doaj +1 more source
Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]
, 2015 Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien +6 more
core +2 more sources
Journal of Animal Ecology, Volume 95, Issue 2, Page 296-312, February 2026.As West Africa urbanises, the risk of Lassa fever may paradoxically decrease. We found the invasive house mouse, a dominant urban species, outcompetes and displaces the primary Lassa virus host. Considering these species interactions is critical for accurately predicting future zoonotic disease patterns.
David Simons +13 more
wiley +1 more source
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.
PLoS Pathogens, 2015 Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection and ...
Rami Sommerstein +17 more
doaj +1 more source
Protein Science, Volume 34, Issue 12, December 2025.Abstract Human transferrin receptor 1 (TfR) is essential for cellular iron homeostasis by internalizing the iron carrier proteins transferrin and ferritin. It is also an entry point for various pathogens, such as South American hemorrhagic fever caused by arenaviruses and the malaria parasite Plasmodium vivax, which utilize TfR to gain access to cells.
Anuthariq Alikkam Veetil +5 more
wiley +1 more source
PLoS Pathogens, 2009 Arenaviruses are the causative pathogens of severe hemorrhagic fever and aseptic meningitis in humans, for which no licensed vaccines are currently available. Pathogen heterogeneity within the Arenaviridae family poses a significant challenge for vaccine
Maya F Kotturi +17 more
doaj +1 more source
Purification and electron cryomicroscopy of coronavirus particles. [PDF]
, 2008 Intact, enveloped coronavirus particles vary widely in size and contour, and are thus refractory to study by traditional structural means such as X-ray crystallography. Electron microscopy (EM) overcomes some problems associated with particle variability
Adair, Brian D +3 more
core +1 more source