Results 41 to 50 of about 8,104 (224)
A new arenavirus in a cluster of fatal transplant-associated diseases [PDF]
, 2008 Three patients who received visceral-organ transplants from a single donor on the same day died of a febrile illness 4 to 6 weeks after transplantation.
Palacios, Gustavo F. +17 more
core +3 more sources
The Current State of Vaccine Development for Specific Prophylactics of Arenaviral Hemorrhagic Fevers
Проблемы особо опасных инфекций, 2018 Presently, the Arenavirus genus (Arenaviridae family) includes 26 individual species of viruses. It is divided into two main groups – Old World arenaviruses and New World arenaviruses.
T. E. Sizikova +3 more
doaj +1 more source
Analyzing Machupo virus-receptor binding by molecular dynamics simulations [PDF]
, 2014 In many biological applications, we would like to be able to computationally predict mutational effects on affinity in protein-protein interactions. However, many commonly used methods to predict these effects perform poorly in important test cases.
Ellington, Andrew D. +3 more
core +2 more sources
MOLECULAR-BIOLOGICAL PECULIARITIES OF ARENAVIRUS REPRODUCTION IN SENSITIVE CELLS
Проблемы особо опасных инфекций, 2017 The Arenaviridae family consists of a large group of single strand ambisense RNA viruses that are separated phylogenetically, serologically and geographically into Old World and New World viruses.
T. E. Sizikova +4 more
doaj +1 more source
Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]
, 2013 Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia +5 more
core +3 more sources
Journal of Virology, 2020 Arenavirus NPs contain a highly conserved DEDDh ExoN motif, through which LASV NP degrades virus-derived, immunostimulatory dsRNA in biochemical assays to eliminate the danger signal and inhibit the innate immune response.
E. Mateer +4 more
semanticscholar +1 more source
Pathogens, 2020 Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up to 300,000 new infections and 5000 deaths each year across Western Africa.
Rachel A. Sattler +3 more
doaj +1 more source
A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease. [PDF]
, 2016 UNLABELLED: Arenaviruses are emerging viruses including several causative agents of severe hemorrhagic fevers in humans. The advent of next-generation sequencing technology has greatly accelerated the discovery of novel arenavirus species.
Bergeron, E. +7 more
core +1 more source
Emerging Infectious Diseases, 2011 To investigate arenavirus in Zambia, we characterized virus from the kidneys of 5 arenavirus RNA–positive rodents (Mastomys natalensis) among 263 captured.
Akihiro Ishii +8 more
doaj +1 more source
Rational design of universal immunotherapy for TfR1-tropic arenaviruses
Nature Communications, 2020 Certain arenaviruses that circulate in rodent populations can cause life-threatening hemorrhagic fevers when they infect humans. Due to their efficient transmission, arenaviruses pose a severe risk for outbreaks and might be exploited as biological ...
H. Cohen-Dvashi +9 more
semanticscholar +1 more source