Results 91 to 100 of about 10,357 (212)
Arginase, ornithine carbamoyl transferase (OCT) and arginine deiminase activities were found in cell-free extracts of Nostoc PCC 73102, a free-living cyanobacterium originally isolated from the cycad Macrozamia.
García-Reina, Guillermo +3 more
core +1 more source
Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes
Protein citrullination, driven by peptidyl arginine deiminases (PAD2, PAD4), is linked to multiple diseases. Using a combinatorial peptide library and advanced mass spectrometry, we reveal distinct substrate selectivity profiles of PAD2 and PAD4. While PAD2 broadly citrullinates arginine‐containing peptides, PAD4 is highly sequence‐restricted, with ...
Adina Borbély +6 more
wiley +1 more source
คณะผู้วิจัยทำการสังเคราะห์ชิ้นส่วน DNA จากแบคทีเรียแลกติกไอโซเลท SC8 ซึ่งเป็นสายพันธุ์ที่ใช้ในอุตสาหกรรมอาหาร จากการวิเคราะห์ลำดับ DNA ขนาด 4149 bp ดังกล่าวพบว่าประกอบด้วย 3 open reading frames ได้แก่ arcA arcB และ arcD (บางส่วน) ตามลำดับ เมื่อทำการว ...
อังประภาพรชัย, ประวัติ +1 more
core
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Arginine deiminase gene therapy for disordered proteins
The invention relates to compositions comprising arginine deiminase and their use in a method of reducing aggregation of disordered protein in a ...
Nash, Kevin Ron, Lee, Daniel C.
core
Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang +7 more
wiley +1 more source
Study on the role of protein deiminases in the nervous system
"Study on the role of protein deiminases in the nervous system" Citrullination (deimination) is the conversion of protein-bound arginine to citrulline. Citrullination is catalyzed by a family of calcium-dependent enzymes, the peptidylarginine deiminases (
MILLARTE, VALENTINA
core
Arginine deiminase and other antiangiogenic agents inhibit unfavorable neuroblastoma growth: potentiation by irradiation [PDF]
In spite of aggressive therapy, children suffering from neuroblastoma have a poor prognosis. Therapeutic failure is most often observed in neuroblastomas with unfavorable features, including amplification/over-expression of the N-myc oncogene, rapid ...
Havers, W. +11 more
core +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source
Arginine deiminase inhibits cell proliferation by arresting cell cycle and inducing apoptosis
We have previously demonstrated that arginine deiminase inhibits the proliferation of vascular endothelial cells, but the mechanisms leading to growth inhibition have remained unclear. We report here that low concentrations of arginine deiminase purified
von Recklinghausen, G. +7 more
core

