Results 11 to 20 of about 43,543 (282)
A Prokaryotic Twist on Argonaute Function [PDF]
Life, 2015 Argonaute proteins can be found in all three domains of life. In eukaryotic organisms, Argonaute is, as the functional core of the RNA-silencing machinery, critically involved in the regulation of gene expression.
Sarah Willkomm +3 more
doaj +3 more sources
Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity [PDF]
eLifeRNA interference (RNAi) is a conserved pathway that utilizes Argonaute proteins and their associated small RNAs to exert gene regulatory function on complementary transcripts.
Shihui Chen, Carolyn Marie Phillips
doaj +2 more sources
Functional diversification of Argonautes in nematodes: an expanding universe [PDF]
, 2013 In the last decade, many diverse RNAi (RNA interference) pathways have been discovered that mediate gene silencing at epigenetic, transcriptional and post-transcriptional levels. The diversity of RNAi pathways is inherently linked to the evolution of Ago
Amy H. Buck, Mark Blaxter
openalex +3 more sources
Structure of the guide-strand-containing argonaute silencing complex
Nature, 2008 Yanli Wang +2 more
exaly +3 more sources
RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection
Frontiers in Microbiology, 2023 RNA interference (RNAi) is one of the important defense responses against viral infection, but its mechanism and impact remain unclear in mycovirus infections.
Yinhui Jiang +17 more
doaj +1 more source
eLife, 2022 MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly understood ...
Sean E McGeary +4 more
doaj +1 more source
Understanding miRNA Based Gene Regulation in Parkinson’s Disease: An in silico Approach [PDF]
International Journal Bioautomation, 2020 Parkinson’s disease (PD) is the second most common neurodegenerative disorder, mainly characterized by depletion or insufficient release of dopaminergic neurons in substantia nigra of the midbrain.
Surya Narayan Rath, Manorama Patri
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Biomolecules, 2022 Prokaryotic Argonautes (pAgos) from mesophilic bacteria are attracting increasing attention for their genome editing potential. So far, it has been reported that KmAgo from Kurthia massiliensis can utilize DNA and RNA guide of any sequence to effectively
Xiaoman Jiang +3 more
doaj +1 more source
Barley Anther and Meiocyte Transcriptome Dynamics in Meiotic Prophase I
Frontiers in Plant Science, 2021 In flowering plants, successful germinal cell development and meiotic recombination depend upon a combination of environmental and genetic factors. To gain insights into this specialized reproductive development program we used short- and long-read RNA ...
Abdellah Barakate +13 more
doaj +1 more source
ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis. [PDF]
, 2014 Small RNAs (sRNAs) are loaded into ARGONAUTE (AGO) proteins to induce gene silencing. In plants, the 5'-terminal nucleotide is important for sRNA sorting into different AGOs.
Carbonell, Alberto +9 more
core +5 more sources