Results 11 to 20 of about 25,854 (244)

MicroRNA 3′-compensatory pairing occurs through two binding modes, with affinity shaped by nucleotide identity and position

open access: yeseLife, 2022
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly understood ...
Sean E McGeary   +4 more
doaj   +1 more source

Analysis of Genetic Variation of Rice Straw Characteristics and Its Influence on Biomass. [PDF]

open access: yesPlant Direct
ABSTRACT Rice straw is a key source of lignocellulosic biomass. GWAS can be used to identify genetic loci controlling stem morphological traits that influence biomass. This study aimed to investigate the genotypic diversity of rice straw internodes through GWAS, using 34,232 single‐nucleotide polymorphic sites with a minor allelic frequency (MAF ...
Mohamadiaza M   +4 more
europepmc   +2 more sources

Argonaute and Argonaute-Bound Small RNAs in Stem Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Small RNAs are essential for a variety of cellular functions. Argonaute (AGO) proteins are associated with all of the different classes of small RNAs, and are indispensable in small RNA-mediated regulatory pathways. AGO proteins have been identified in various types of stem cells in diverse species from plants and animals.
Zhai, Lihong   +7 more
openaire   +4 more sources

Circular and Micro RNAs from Arabidopsis thaliana Flowers Are Simultaneously Isolated from AGO-IP Libraries

open access: yesPlants, 2019
Competing endogenous RNAs (ceRNAs) are natural transcripts that can act as endogenous sponges of microRNAs (miRNAs), modulating miRNA action upon target mRNAs. Circular RNAs (circRNAs) are one among the various classes of ceRNAs. They are produced from a
Érika Frydrych Capelari   +3 more
doaj   +1 more source

Argonaute Reformatting [PDF]

open access: yesMolecular Cell, 2013
In this issue of Molecular Cell, De et al. (2013) report that highly complementary targets promote release of small RNAs from effector Argonaute complexes, thus providing mechanistic insights into regulation of small RNA stability and implications for siRNA design.
openaire   +2 more sources

AtXRN4 Affects the Turnover of Chosen miRNA*s in Arabidopsis

open access: yesPlants, 2020
Small RNA (sRNA) turnover is a key but poorly understood mechanism that determines the homeostasis of sRNAs. Animal XRN genes contribute the degradation of sRNAs, AtXRN2 and AtXRN3 also contribute the pri-miRNA processing and miRNA loop degradation in ...
Yan Liu   +7 more
doaj   +1 more source

The Argonautes [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2006
RNA interference (RNAi) has been greatly exploited in recent years as an increasingly effective tool to study gene function by gene silencing. The introduction of exogenous double-stranded RNA (dsRNA) into a cell can trigger this gene silencing process.
openaire   +2 more sources

NbNAC42 and NbZFP3 Transcription Factors Regulate the Virus Inducible NbAGO5 Promoter in Nicotiana benthamiana

open access: yesFrontiers in Plant Science, 2022
Plant argonautes (AGOs) play important roles in the defense responses against viruses. The expression of Nicotiana benthamiana AGO5 gene (NbAGO5) is highly induced by Bamboo mosaic virus (BaMV) infection; however, the underlying mechanisms remain elusive.
Yuan-Dun Ke   +11 more
doaj   +1 more source

Innate Immunity Activation and RNAi Interplay in Citrus Exocortis Viroid—Tomato Pathosystem

open access: yesViruses, 2018
Although viroids are the smallest and simplest plant pathogens known, the molecular mechanisms underlying their pathogenesis remain unclear. To unravel these mechanisms, a dual approach was implemented consisting of in silico identification of potential ...
Thibaut Olivier, Claude Bragard
doaj   +1 more source

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