Results 71 to 80 of about 43,543 (282)

Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]

open access: yes, 2013
RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif   +2 more
core   +3 more sources

Differentiation among the ARGONAUTES [PDF]

open access: yesThe Plant Cell, 2010
Noncoding RNAs, including small RNAs (sRNAs), act in an astonishing variety of cellular processes, including gene expression, heterochromatin dynamics, and regulation of development (reviewed in [Amaral et al., 2008][1]), and ARGONAUTE (AGO) proteins are key effectors of these processes ...
openaire   +3 more sources

Hsa_circ_0026782 Acts as a “Molecular Break” of CREB1‐Mediated Transcription by Promoting Its Phosphorylation at Ser142 That Prevents Keloid Progression

open access: yesAdvanced Science, EarlyView.
Model for the role of hsa_circ_0026782/p‐CREB1 (Ser142) played in keloid. Hsa_circ_0026782 is derived from back‐splicing of ITGA7 exon 4. When hsa_circ_0026782 binds to CREB1, the exposure of the bZIP domain and dimerization of CREB1 are promoted (upper left).
Xin‐Cao Zhong   +10 more
wiley   +1 more source

In Silico Identification, Phylogenetic and Bioinformatic Analysis of Argonaute Genes in Plants

open access: yesInternational Journal of Genomics, 2014
Argonaute protein family is the key players in pathways of gene silencing and small regulatory RNAs in different organisms. Argonaute proteins can bind small noncoding RNAs and control protein synthesis, affect messenger RNA stability, and even ...
Khaled Mirzaei   +3 more
doaj   +1 more source

A Forward Genetics Strategy for High‐Throughput Gene Identification via Precise Image‐Based Phenotyping of an Indexed EMS Mutant Library

open access: yesAdvanced Science, EarlyView.
The GeneHunter‐Gene‐Level Association (GH‐GLA) pipeline enables high‐throughput gene identification in an indexed EMS population of wheat cultivar KN9204. It identifies 5905 trait‐associated wheat genes and validates key regulators of kernel weight and spikelet architecture via gene editing and haplotype analysis.
Haojie Wang   +16 more
wiley   +1 more source

Lost and Found: Piwi and Argonaute Pathways in Flatworms

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Platyhelminthes comprise one of the major phyla of invertebrate animals, inhabiting a wide range of ecosystems, and one of the most successful in adapting to parasitic life.
Santiago Fontenla   +2 more
doaj   +1 more source

Emerging connections between small RNAs and phytohormones [PDF]

open access: yes, 2020
Small RNAs (sRNAs), mainly including miRNAs and siRNAs, are ubiquitous in eukaryotes. sRNAs mostly negatively regulate gene expression via (post-)transcriptional gene silencing through DNA methylation, mRNA cleavage, or translation inhibition.
Dubois, Marieke   +3 more
core   +2 more sources

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou   +5 more
wiley   +1 more source

Antiviral roles of plant ARGONAUTES

open access: yesCurrent Opinion in Plant Biology, 2015
ARGONAUTES (AGOs) are the effector proteins functioning in eukaryotic RNA silencing pathways. AGOs associate with small RNAs and are programmed to target complementary RNA or DNA. Plant viruses induce a potent and specific antiviral RNA silencing host response in which AGOs play a central role.
CARBONELL, ALBERTO, Carrington, James C.
openaire   +4 more sources

Advances in miRNA research: Unraveling the complexities of gene regulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

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