Results 81 to 90 of about 30,324 (235)
Identification and comparison of orthologous argonaute gene sequences in bananas / Pui Han Pin [PDF]
, 2009 The Argonaute proteins are key components in the effector complex of RNA silencing pathways which interact with small RNAs to mediate sequence specific silencing of nucleic acid targets (reviewed in Carmell et al., 2002; Lingel & Izaurralde, 2004 ...
Pui, Han Pin
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Inferring targeting modes of Argonaute-loaded tRNA fragments
, 2019 Transfer RNA fragments (tRFs) are an emerging class of small RNA molecules derived from mature or precursor tRNAs. They are found across a wide range of organisms and tissues, in small RNA fraction or loaded to Argonaute in numbers comparable to ...
Spyros Karaiskos (3580580) +2 more
core +1 more source
The role of TNRC6 proteins in gene silencing [PDF]
, 2013 Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
core +1 more source
Cell Proliferation, EarlyView.A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang +11 more
wiley +1 more source
Unravelling the developmental and functional significance of an ancient Argonaute duplication [PDF]
, 2020 MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target regulation is considered crucial for animal physiology and development.
Fridrich, A +9 more
core +1 more source
Progress in micro RNA focused research in endocrinology
Endocrine Regulations, 2016 Micro RNAs (miRNAs) are small regulatory molecules of increasing biologists’ interest. miRNAs, unlikely mRNA, do not encode proteins. It is a class of small double stranded RNA molecules that via their seed sequence interact with mRNA and inhibit its ...
Voglova K., Bezakova J., Herichova Iveta
doaj +1 more source
Argonaute proteins: Structural features, functions and emerging roles
Journal of Advanced Research, 2020 Argonaute proteins are highly conserved in almost all organisms. They not only involve in the biogenesis of small regulatory RNAs, but also regulate gene expression and defend against foreign pathogen invasion via small RNA-mediated gene silencing ...
Jin'en Wu +3 more
doaj +1 more source
The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis
The FEBS Journal, EarlyView.H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo +8 more
wiley +1 more source
DNA-guided DNA interference by a prokaryotic Argonaute
, 2014 This disclosure provides for compositions and methods for the use of designed nucleic acid-targeting nucleic acids, Argonautes, and complexes thereof. In one aspect, the disclosure provides for a composition comprising: a complex comprising: an Argonaute
Oost, J., van der, Swarts, D.C.
core
Effect of Non-Coding RNA on Post-Transcriptional Gene Silencing of Alzheimer Disease [PDF]
, 2010 A large amount of hidden biological information is contained in the human genome, which is not expressed or revealed in the form of proteins; the usual end product form of gene expression.
Premkumar P +7 more
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